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Effects of 21 days of bedrest on human skeletal muscle gene expression

Metadata Updated: April 24, 2025

The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic bedrest (NBR) with muscle unloading for 21 days this is a substudy of tha PlanHab-study which apart from normoxic bedrest also involved hypoxic bedrest and hypoxic ambulation. Throughout both bedrest interventions each subject remained in a horizontal position at all times. He was allowed one pillow for the head and to occasionally lean on an elbow while eating or being transferred to a gurney. Muscular exercise was prohibited. During the HAMB confinement each subject was allowed to move freely within the hypoxic area. To mimic a normal level of physical activity subjects performed 30 minutes of low-to-moderate-intensity exercise twice daily. Muscle samples from Vastus lateralis.

Access & Use Information

Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

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Dates

Metadata Created Date January 31, 2023
Metadata Updated Date April 24, 2025
Data Update Frequency irregular

Metadata Source

Harvested from NASA Data.json

Additional Metadata

Resource Type Dataset
Metadata Created Date January 31, 2023
Metadata Updated Date April 24, 2025
Publisher National Aeronautics and Space Administration
Maintainer
Identifier nasa_genelab_GLDS-195_gk5i-fxnp
Data First Published 2018-09-05
Data Last Modified 2025-04-23
Category Earth Science
Public Access Level public
Data Update Frequency irregular
Bureau Code 026:00
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id 8306c346-201b-4f76-aeee-d4f0bdafb4b1
Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
Harvest Source Title NASA Data.json
Homepage URL https://data.nasa.gov/dataset/effects-of-21-days-of-bedrest-on-human-skeletal-muscle-gene-expression
Program Code 026:005
Source Datajson Identifier True
Source Hash 81c313b57b68ed82ac9b95adba9fcdd7454808f0e63483d5d8fbc64fa7f6fc86
Source Schema Version 1.1

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