12 datasets found
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Federal
Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry
U.S. Environmental Protection Agency —
Supplementary material for "Kreutz, A.; Clifton, M.S.; Henderson, W.M.; Smeltz, M.G.; Phillips, M.; Wambaugh, J.F.; Wetmore, B.A. Category-Based Toxicokinetic... -
Federal
Dataset for 'Development of a bioprinter-based method for incorporating metabolic competence into high-throughput in vitro assays'
U.S. Environmental Protection Agency —
Data for Hopperstad K and Deisenroth C (2023) Development of a bioprinter-based method for incorporating metabolic competence into high-throughput in vitro assays.... -
Federal
Targeted Per- and Polyfluoroalkyl Substances (PFAS) Assessments for High Throughput Screening: Analytical and Testing Considerations to Inform a PFAS Stock Quality Evaluation Framework
U.S. Environmental Protection Agency —
Data for "Smeltz MG, Clifton MS, Henderson WM, McMillan L, Wetmore BA. Targeted Per- and Polyfluoroalkyl substances (PFAS) assessments for high throughput screening:... -
Federal
Bayesian inference of chemical exposures from NHANES urine biomonitoring data
U.S. Environmental Protection Agency —
Data and files for "Stanfield, Z., Setzer, R.W., Hull, V. et al. Bayesian inference of chemical exposures from NHANES urine biomonitoring data. J Expo Sci Environ... -
Federal
High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells
U.S. Environmental Protection Agency —
Supplemental datafiles for journal article 'High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells'. -
Federal
Dataset for 'From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow'
U.S. Environmental Protection Agency —
Data for Reardon AJF, et al., From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a... -
Federal
Cross-species molecular docking method to support predictions of species susceptibility to chemical effects
U.S. Environmental Protection Agency —
The advancement of protein structural prediction tools, exemplified by AlphaFold and Iterative Threading ASSEmbly Refinement, has enabled the prediction of protein... -
Federal
In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories
U.S. Environmental Protection Agency —
Dataset for "Crizer, D.M.; Rice, J.R.; Smeltz, M.G.; Lavrich, K.S.; Ravindra, K.; Wambaugh, J.F.; DeVito, M.; Wetmore, B.A. In Vitro Hepatic Clearance Evaluations of... -
Federal
Datasets associated with journal article 'Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example' by Nyffeler, J, et.al.
U.S. Environmental Protection Agency —
We evaluated the Templated Oligo with Sequencing Readout (TempO-Seq) assay for High-throughput transcriptomic screening of a small set of environmental chemicals.... -
Federal
Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing
U.S. Environmental Protection Agency —
Data and code for "Grace Patlewicz, Ann M. Richard, Antony J. Williams, Richard S. Judson, Russell S. Thomas, Towards reproducible structure-based chemical categories... -
Federal
Cross-species comparisons of plasma binding and considerations for data evaluation
U.S. Environmental Protection Agency —
Dataset for "Cross-species comparisons of plasma binding and considerations for data evaluation.". This dataset is associated with the following publication: Lynn,... -
Federal
Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays
U.S. Environmental Protection Agency —
Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays'...
12 datasets found