12 datasets found
-
Federal
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity
National Aeronautics and Space Administration —
Efficient generation of cardiomyocytes from human pluripotent stem cells is critical for their regenerative applications. Microgravity and 3D culture can profoundly... -
Federal
HARV replication of the BRIC-23 Bacillus subtilis spaceflight
National Aeronautics and Space Administration —
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This... -
Federal
Gravitational signature of synchronized cell cultures in particular cell cycle stages
National Aeronautics and Space Administration —
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall... -
Federal
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under Microgravity
National Aeronautics and Space Administration —
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls.... -
Federal
Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression
National Aeronautics and Space Administration —
This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli... -
Federal
HARV replication of the BRIC-21 Bacillus subtilis spaceflight samples
National Aeronautics and Space Administration —
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This... -
Federal
Effect of microgravity on HUVECs (Human Umbilical vein Endothelial cells) cells and its transcriptome analysis.
National Aeronautics and Space Administration —
Adaptation of humans in low gravity conditions is a matter of utmost importance when efforts are on to a gigantic leap in human space expeditions for tourism and... -
Federal
Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity
National Aeronautics and Space Administration —
Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety health and performance of the crewmembers.... -
Federal
A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells
National Aeronautics and Space Administration —
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the... -
Federal
Transcription profiling of mouse osteoblasts under static vs simulated microgravity
National Aeronautics and Space Administration —
The total RNA was extracted from 2T3 pre-osteoblast cells exposed to static or simulated microgravity (Rotating Wall Vessel) conditions. The RNA was then sent to... -
Federal
A study of alterations DNA epigenetic modifiincations (5mC and 5hmC) influenced by simulated microgravity in human lymphoblastoid cells
National Aeronautics and Space Administration —
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the... -
Federal
T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during...
12 datasets found