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A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells

Metadata Updated: April 24, 2025

Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6 lymphoblastoid cells upon exposure to micro-gravity conditions. The results reported here indicate that simulated microgravity alters methylation patterns in a limited way and subsequently the expression of genes involved in stress response like ATF3 FBXO17 MAP3K13 and VCL in TK6 cells. Overall design: Examination of RNA-seq with 2 replicates each for 1 cell type

Access & Use Information

Public: This dataset is intended for public access and use. License: us-pd

Downloads & Resources

Dates

Metadata Created Date January 31, 2023
Metadata Updated Date April 24, 2025
Data Update Frequency irregular

Metadata Source

Harvested from NASA Data.json

Additional Metadata

Resource Type Dataset
Metadata Created Date January 31, 2023
Metadata Updated Date April 24, 2025
Publisher National Aeronautics and Space Administration
Maintainer
Identifier nasa_genelab_GLDS-91_43bs-bf56
Data First Published 2021-05-21
Data Last Modified 2025-04-23
Category Earth Science
Public Access Level public
Data Update Frequency irregular
Bureau Code 026:00
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id 9c8e0db8-3123-4922-8567-cd454b65abd2
Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
Harvest Source Title NASA Data.json
Homepage URL https://data.nasa.gov/dataset/a-study-of-gene-expression-influenced-by-simulated-microgravity-in-human-lymphoblastoid-ce
License http://www.usa.gov/publicdomain/label/1.0/
Program Code 026:005
Source Datajson Identifier True
Source Hash 0b9d02d023258f99ee574ebb5743d9f693ec647bc8f6d493121da4e8f8cfc285
Source Schema Version 1.1

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