239 datasets found
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Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Global gene expression analysis highlights microgravity sensitive key genes in soleus and EDL of 30 days space flown mice
National Aeronautics and Space Administration —
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in... -
Federal
Expression Data from International C. elegans Experiment 1st (ICE-FIRST)
National Aeronautics and Space Administration —
The effect of microgravity on gene expression in C.elegans was comprehensively analysed by DNA microarray (Agilent). Overall design: Mix staged C. elegans N2 was... -
Federal
Comparative gene expression analysis in the Arabidopsis thaliana root apex using RNA-seq and microarray transcriptome profiles
National Aeronautics and Space Administration —
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Federal
DNA copy number analysis from mice with radiation-induced acute myeloid leukemia
National Aeronautics and Space Administration —
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using... -
Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
Effects of spaceflight on murine skeletal muscle gene expression
National Aeronautics and Space Administration —
Spaceflight results in a number of adaptations to skeletal muscle including atrophy and shifts towards faster muscle fiber types. To identify changes in gene... -
Federal
Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle
National Aeronautics and Space Administration —
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of... -
Federal
Dynamic gene expression response to altered gravity in human T cells (parabolic flight)
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles... -
Federal
Transcription profiling of rat response to changes in developmental stage - 3 types of tissue 3 gravity conditions 2 developmental conditions
National Aeronautics and Space Administration —
Transcriptional crosstalk between mammary gland liver and adipose tissue Experiment Overall Design: Pregnant and Lactating rats exposed to 3 gravity conditions -
Federal
Rodent Research-3-CASIS: Mouse eye transcriptomic and proteomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
A whole-genome microarray study of Arabidopsis thaliana cell cultures exposed to microgravity for 5 days on board of Shenzhou 8
National Aeronautics and Space Administration —
Arabidopsis thaliana wild type cell cultures were exposed to a 5-day space flight onboard of Shenzhou 8 to identify microgravity and space effect related gene... -
Federal
Gene expression profiling of C. elegans under various thermal conditions
National Aeronautics and Space Administration —
To realistically evaluate the effects of the environment in space it is necessary to understand the effects of external factors during sample transport from Earth to... -
Federal
CDRH Advisory Meeting Materials Archive
U.S. Department of Health & Human Services —
This database contains historical information about CDRH Advisory Committees and Panel meetings through 2008, including summaries and transcripts. -
Federal
Approved Animal Drug Products (Green Book)
U.S. Department of Health & Human Services —
On November 16, 1988, the President of the United States signed into law the Generic Animal Drug and Patent Restoration Act (GADPTRA). Among its major provisions, the... -
Federal
Osteocytes transcriptome is altered during spaceflight
National Aeronautics and Space Administration —
Bone loss is one of the major health problems for astronauts during long-term spaceflight and for patients during prolonged bed rest or paralysis. Growing evidence... -
Federal
Comparison of gene expression profiles of normal human bronchial epithelial cells in 2D and 3D cultural conditions
National Aeronautics and Space Administration —
The experiment is part of a project to study DNA repair process after ionizing radiation in organotypic 3-dimentional human bronchial epithlial cell culture. Human... -
Federal
Microgravity effect on C. elegans N2/VC (CERISE 8days)
National Aeronautics and Space Administration —
Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8 days in the Japanese... -
Federal
Dynamic gene expression response to altered gravity in human myelomonocytic U937 cells [sounding rocket]
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to... -
Federal
Bacillus subtilis spores PROTECT experiment Space-exposed and Mars-exposed vs. Earth-control
National Aeronautics and Space Administration —
Because of their ubiquity and resistance to spacecraft decontamination bacterial spores are considered likely potential forward contaminants on robotic missions to...
239 datasets found
