6 datasets found
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Federal
The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM) recent views
U.S. Environmental Protection Agency —
This dataset contains model code and supporting analysis files necessary to evaluate the impact of variability in human hepatic scaling factors. Variation in scaling... -
Federal
Predicting Potential Human Health Risk with the Tox21 10k Library recent views
U.S. Environmental Protection Agency —
This study represents the first report applying IVIVE approaches and exposure comparisons using the entirety of the Tox21 federal collaboration chemical screening... -
Federal
Comparison of In Vivo Derived and Scaled In Vitro Metabolic Rate Constants for Several Volatile Organic Compounds (VOCs) recent views
U.S. Environmental Protection Agency —
Data sets in the context of this project are the model files, model input parameter sets, and data generated at the US EPA/ORD/National Health and Environmental... -
Federal
Dose Response, Dosimetric, and Metabolic Evaluations of Replacement PFAS Perfluoro-(2,5,8-trimethyl-3,6,9-trioxadodecanoic) Acid (HFPO-TeA) recent views
U.S. Environmental Protection Agency —
The supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/toxics11120951/s1. Text S1: Chemicals; Text S2: Thyroid Hormone Chemicals and... -
Federal
Honda_Wambaugh_Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions recent views
U.S. Environmental Protection Agency —
All relevant data are within the manuscript, its Supporting Information files, and the httk R software package v1.9.2. This dataset is associated with the following... -
Federal
Predictive Models for In Vitro Toxicokinetic Parameters to Inform High-throughput Risk-assessment_Prachi recent views
U.S. Environmental Protection Agency —
The data used in this analysis was obtained from published literature and available through the high-throughput toxicokinetic (HTTK) R package. The dataset consists...
6 datasets found