36 datasets found
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Federal
Datasets for 'Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals'
U.S. Environmental Protection Agency —
First, we curated and selected experimental animal toxicity data and split them into two distinct data sets covering general noncancer effects and... -
Federal
Developmental toxicity of PFO4DA and PFO5DoA assessed using hepatic transcriptomics and serum metabolomics
U.S. Environmental Protection Agency —
Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the... -
Federal
Bridging in vitro and in vivo inhalation toxicity: Volatile organic compounds elicit similar transcriptomic points of departure in human airway cells and mouse respiratory tract
U.S. Environmental Protection Agency —
The revised paper dataset includes data shown in the main paper and supplemental file and are derived from Excel files associated with this Science Hub entry. The... -
Federal
Gupta 2025 Dipentyl phthalate testis dose response dataset
U.S. Environmental Protection Agency —
Dataset includes summary data for all endpoints measured in the experiments reported in the manuscript. This dataset is associated with the following publication:... -
Federal
An aggregated dataset of serially collected influenza A virus morbidity and titer measurements from virus-infected ferrets.
U.S. Department of Health & Human Services —
Data from influenza A virus (IAV) infected ferrets (Mustela putorius furo) provides invaluable information towards the study of novel and emerging viruses that pose a... -
Federal
Conley_2021_NBP2_Dev_tox_Dataset_2022-1-10.xlsx
U.S. Environmental Protection Agency —
Dataset contains summary data (mean +/- error) for all endpoints measured in published studies. This dataset is associated with the following publication: Conley, J.,... -
Federal
Gray 2025 Phthalate transcriptomic and apical points of departure dataset
U.S. Environmental Protection Agency —
Dataset includes all endpoint measurements from studies described in the manuscript and SAS code for statistical analyses of data. This dataset is associated with the... -
Federal
Gestational Exposure to Perchlorate in the rat: Thyroid Hormones in Fetal Thyroid Gland, Serum, and Brain
U.S. Environmental Protection Agency —
This dataset contains results from rodent study. Thyroid hormones and brain endpoints are reported for pregnant rat dams and progeny on gestational day 20 following... -
Federal
Ammonium Perchlorate - Serum dosimetry, neurotoxicity and resilience of the neonatal rat thyroid system
U.S. Environmental Protection Agency —
Perchlorate is an environmental contaminant that interferes with iodine uptake via the NIS transporter into the thyroid gland, reducing thyroid hormone (TH)... -
Federal
Using Zebrafish to Screen Developmental Toxicity of Per- and Polyfluoroalkyl Substances (PFAS)
U.S. Environmental Protection Agency —
Figure S1: BMC curves. Table S1: Fish assessments. Table S2: Data to make visualization of toxicity (Figure 3). Table S3: Data to make BMC curves. This dataset is... -
Federal
Intra- and inter-laboratory evaluation of an assay of soil arsenic relative bioavailability in mice
U.S. Environmental Protection Agency —
Data were generated from US EPA Superfund site soil samples. This dataset is not publicly accessible because: EPA cannot release personally identifiable information... -
Federal
An aggregated dataset of day 3 post-inoculation viral titer measurements from influenza A virus-infected ferret tissues
U.S. Department of Health & Human Services —
Data from influenza A virus (IAV) infected ferrets (Mustela putorius furo) provides invaluable information towards the study of novel and emerging viruses that pose a... -
Federal
PFESABP2v01
U.S. Environmental Protection Agency —
Data for individual animals used to create the information demonstrated in Table 1 of the manuscript, including PFESA BP2 serum and liver concentrations and serum... -
Federal
Data for "Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain"
U.S. Environmental Protection Agency —
Raw data accompanying "Thyroid Hormone Action Controls Multiple Components of Cell Junctions at the Ventricular Zone in the Newborn Rat Brain". This dataset is... -
Federal
In vivo plasma concentration for lindane after 6 hour exposure in human skin
U.S. Environmental Protection Agency —
Dataset is a time course description of lindane disappearance in blood plasma after dermal exposure in human volunteers. This dataset is associated with the following... -
Federal
dicyclohexyl phthalate fetal testis gene expression data
U.S. Environmental Protection Agency —
dicyclohexyl phthalate fetal testis data -
Federal
Conley 2024 Maternal and fetal effects of PFO5DoA and PFO4DA Dataset
U.S. Environmental Protection Agency —
Summary data (mean, standard error, sample size) for all maternal and fetal endpoints reported in the manuscript from experiments with the novel, long-chain PFAS... -
Federal
Iodine Deficiency Exacerbates Thyroidal and Neurological Effects of Developmental Perchlorate Exposure in the Neonatal and Adult Rat
U.S. Environmental Protection Agency —
Thyroid hormones status, brain molecular and structural changes, and neurobehavioral impairments following maternal exposure to perchlorate in a rodent pregnancy... -
Federal
Assessing utility of thyroid in vitro screening assays through comparisons to observed impacts in vivo
U.S. Environmental Protection Agency —
Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro... -
Federal
Structural Malformations in Brain Accompany Developmental Perchlorate Exposure in Rodents
U.S. Environmental Protection Agency —
Structural defects in the rat brain associated with maternal exposure to ammonium perchlorate accompanied reductions in circulating levels of thyroid hormone in the...
36 datasets found