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Federal
Triclosan Hershberger H295 data
U.S. Environmental Protection Agency —
Triclosan data from Hershberger experiment using castrated male rats. Data includes accessory sex tissue mean weights and thyroid gland weight following exposure to... -
Federal
Evaluating potential developmental toxicity of perfluoroalkyl and polyfluoroalkyl substances in Xenopus laevis embryos and larvae
U.S. Environmental Protection Agency —
Dataset for "Degitz SJ, Degoey PP, Haselman JT, Olker JH, Stacy EH, Blanksma C, Meyer S, Mattingly KZ, Blackwell B, Opseth AS, Hornung MW. Evaluating potential... -
Federal
Human Iodotyrosine Deiodinase Inhibition Assay: Screening of ToxCast Phase 1_v2, Phase 2, and e1k Chemical Libraries
U.S. Environmental Protection Agency —
The excel spreadsheet contains the resultant data from an assay for chemical inhibition of human Iodotyrosine Deiodinase (IYD) enzyme activity screened against the... -
Federal
Cross-species molecular docking method to support predictions of species susceptibility to chemical effects
U.S. Environmental Protection Agency —
The advancement of protein structural prediction tools, exemplified by AlphaFold and Iterative Threading ASSEmbly Refinement, has enabled the prediction of protein... -
Federal
Data supporting amphibian thyroid model parameterization
U.S. Environmental Protection Agency —
This dataset was generated to support parameterization of a larval amphibian thyroid axis computational model. Specifically, plasma iodine levels were determined not... -
Federal
Verification of in vivo estrogenic activity for four per- and polyfluoroalkyl substances (PFAS) identified as estrogen receptor agonists via new approach methodologies (v4)
U.S. Environmental Protection Agency —
The dataset includes data from six experiments in which adult male fathead minnows were exposed to five concentrations of a per- or polyfluorinated alkyl substance... -
Federal
Effects of Chronic Exposure to Triclosan on Reproductive and Thyroid Endpoints in the Adult Wistar Female Rat
U.S. Environmental Protection Agency —
This dataset includes the results of a long term adult female rat oral exposure to triclosan and includes hormone, estrous cyclicity, thyroid histology and liver gene...