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Federal
Phenotypic Profiling of 6PPD, 6PPD-Quinone, and Structurally Diverse Antiozonants in RTgill-W1 Cells Using the Cell Painting Assay
U.S. Environmental Protection Agency —
Methods S1–S2 detailing laboratory and data analysis methods; tables describing materials used (Table S1), assay wells excluded from analyses (Table S2), sourcing... -
Federal
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
U.S. Environmental Protection Agency —
In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics... -
Federal
Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data
U.S. Environmental Protection Agency —
** Note to Josh Harrill- I don't have a copy of the final manuscript so could you please add the description of this dataset (just delete this comment and enter or... -
Federal
Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments
U.S. Environmental Protection Agency —
Dataset for Nyffeler et al., 'Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments', Toxicology &... -
Federal
Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay
U.S. Environmental Protection Agency —
Cell Painting is a high-throughput, phenotypic profiling assay that uses fluorescent cytochemistry o visualize a variety of organelles and high-content imaging to... -
Federal
Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays
U.S. Environmental Protection Agency —
Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays'...