-
Federal
Use of soluble MHC class II/peptide multimers to detect antigen-specific T cells in human disease
U.S. Department of Health & Human Services —
Most techniques that identify antigen-specific T cells are dependent on the response of these cells to the relevant antigen in culture. Soluble multimers of MHC... -
Federal
Cellular responses to
U.S. Department of Health & Human Services —
Background Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would... -
Federal
T-cell-mediated control of autoimmunity
U.S. Department of Health & Human Services —
Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging... -
Federal
Rheumatoid synovial CD4
U.S. Department of Health & Human Services —
CD4+ memory T cells (Tm) from rheumatoid arthritis peripheral blood (RAPB) or peripheral blood from normal donors produced IL-2, whereas fewer cells secreted IFN-γ or... -
Federal
Cytokine, activation marker, and chemokine receptor expression by individual CD4
U.S. Department of Health & Human Services —
IL-10, IL-13, IFN-γ, tumor necrosis factor (TNF)-α, LT-α, CD154, and TNF-related activation-induced cytokine (TRANCE) were expressed by 2-20% of rheumatoid arthritis...