30 datasets found for "immunization"
-
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Brain, Western Blot and ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina heterotoma 14 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Hippocampus; ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (Behavioral Assays)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Effects of spaceflight on the immunoglobulin repertoire of unimmunized C57BL/6 mice
National Aeronautics and Space Administration —
Spaceflight has been shown to suppress the adaptive immune response, altering the distribution and function of lymphocyte populations. B lymphocytes express highly... -
Federal
Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influenced by Immune System Transcriptome Modifications from Splenic Tissue
National Aeronautics and Space Administration —
Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological... -
Federal
Comprehensive multi-omics analysis reveals mitochondrial stress as a central biological hub for spaceflight impact
National Aeronautics and Space Administration —
Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (flow cytometry)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice (western blot, histology, and immunohistochemistry)
National Aeronautics and Space Administration —
Purpose: Astronauts traveling beyond low Earth orbit will be exposed to high linear energy transfer charged particles. Because there is concern about the adverse... -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Cortex; ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Transcriptional analysis of kidneys from mice flown on the RR-7 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-7 mission (RR-7) was to study the impact of the space environment on the gut microbiota of two strains of mice and how any... -
Federal
Characterization of mouse ocular responses (Microscopy) to a 35-day (RR-9) spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations - Proteomics data
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
Spaceflight and simulated microgravity conditions increase virulence of Serratia marcescens in the Drosophila melanogaster infection model
National Aeronautics and Space Administration —
While it has been shown that astronauts suffer immune disorders after spaceflight, the underlying causes are still poorly understood and there are many variables to... -
Federal
Drosophila parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids - Drosophila data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina boulardi 17 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Expression data from drosophila melanogaster
National Aeronautics and Space Administration —
Space travel presents unlimited opportunities for exploration and discovery, but requires a more complete understanding of the immunological consequences of long-term... -
Federal
Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice (echocardiogram/ultrasonography)
National Aeronautics and Space Administration —
Purpose: Astronauts traveling beyond low Earth orbit will be exposed to high linear energy transfer charged particles. Because there is concern about the adverse... -
Federal
Drosophila melanogaster gene expression changes after spaceflight.
National Aeronautics and Space Administration —
Gene expression levels were determined in 3rd instar and adult Drosophila melanogaster reared during spaceflight, to elucidate the genetic and molecular mechanisms... -
Federal
Response to Low Shear Modeled Microgravity Indicates Translation of Lactobacillus acidophilus ATCC 4356 Benefits to Spaceflight
National Aeronautics and Space Administration —
The introduction of generally recognized as safe (GRAS) probiotic microbes into the spaceflight food system has the potential for use as a safe, non-invasive, daily...
30 datasets found for "immunization"