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Federal
Diagnostic and treatment characteristics of polycystic ovary syndrome: descriptive measurements of patient perception and awareness from 657 confidential self-reports
U.S. Department of Health & Human Services —
Background This investigation was undertaken to describe patient perception and awareness of the polycystic ovary syndrome (PCOS), the most common cause of... -
Federal
Sex differences in risk factors for coronary heart disease: a study in a Brazilian population
U.S. Department of Health & Human Services —
Background In Brazil coronary heart disease (CHD) constitutes the most important cause of death in both sexes in all the regions of the country and interestingly, the... -
Federal
Prevalence of attention deficit/hyperactivity disorder among adults in obesity treatment
U.S. Department of Health & Human Services —
Background Bariatric patients showing poor "focus" during treatment more often failed to lose weight or maintain reduced weight. Evaluation of these patients... -
Federal
Hospital competition, resource allocation and quality of care
U.S. Department of Health & Human Services —
Background A variety of approaches have been used to contain escalating hospital costs. One approach is intensifying price competition. The increase in price based... -
Federal
Mechanical ventilation in rural ICUs
U.S. Department of Health & Human Services —
Background: In recent years, rural hospitals have expanded their scope of specialized services, which has led to the development and staffing of rural intensive care... -
Federal
The velocity of ultrasound in human primary melanoma tissue - implications for the clinical use of high resolution sonography
U.S. Department of Health & Human Services —
Background Ultrasonography with 20 MHz frequency can be used to estimate tumour thickness preoperatively in malignant melanoma (MM) of the skin. The vertical invasion... -
Federal
Alterations of E-cadherin and β-catenin in gastric cancer
U.S. Department of Health & Human Services —
Background The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the... -
Federal
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol
U.S. Department of Health & Human Services —
Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket.... -
Federal
Weather conditions and sudden sensorineural hearing loss
U.S. Department of Health & Human Services —
Background Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL). We... -
Federal
Practising evidence-based medicine: the design and implementation of a multidisciplinary team-driven extubation protocol
U.S. Department of Health & Human Services —
Background Evidence from recent literature shows that protocol-directed extubation is a useful approach to liberate patients from mechanical ventilation (MV).... -
Federal
Genetic determinants of mammographic density
U.S. Department of Health & Human Services —
Background Changes in breast density are highly correlated with steroid hormone exposure. Materials and methods In a cross-sectional study of 396 Caucasian and... -
Federal
Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrug
U.S. Department of Health & Human Services —
Background Antibody-directed enzyme prodrug therapy (ADEPT) is a promising new approach to deliver anticancer drugs selectively to tumor cells. In this approach, an... -
Federal
Auto-protective redox buffering systems in stimulated macrophages
U.S. Department of Health & Human Services —
Background Macrophages, upon encounter with micro-organisms or stimulated by cytokines, produce various effector molecules aimed at destroying the foreign agents and... -
Federal
Should all patients receive dual chamber pacing ICDs? The rationale for the DAVID trial
U.S. Department of Health & Human Services —
All of the prospective multicenter trials that support the use of implantable defibrillators have used single chamber pacemakers/implantable cardiovertor... -
Federal
The cost-effectiveness of the WINGS intervention: a program to prevent HIV and sexually transmitted diseases among high-risk urban women
U.S. Department of Health & Human Services —
Background We evaluated the cost-effectiveness of the WINGS project, an intervention to prevent HIV and other sexually transmitted diseases among urban women at high... -
Federal
Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices
U.S. Department of Health & Human Services —
Background Recently a hyperthermic rat hippocampal slice model system has been used to investigate febrile seizure pathophysiology. Our previous data indicates that... -
Federal
Binding of the baculovirus very late expression factor 1 (VLF-1) to different DNA structures
U.S. Department of Health & Human Services —
Background Baculovirus genomes encode a gene called very late expression factor 1 (VLF-1) that is a member of the integrase (Int) family of proteins. In this report... -
Federal
Pancreatic hyperamylasemia during acute gastroenteritis: incidence and clinical relevance
U.S. Department of Health & Human Services —
Background Many case reports of acute pancreatitis have been reported but, up to now, pancreatic abnormalities during acute gastroenteritis have not been studied... -
Federal
Association of mesenchymal cells and immunoglobulins with differentiating epithelial cells
U.S. Department of Health & Human Services —
Background Mesenchymal-epithelial interactions play an important role in the physiology and pathology of epithelial tissues. Mesenchymal cells either associate with... -
Federal
The Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial
U.S. Department of Health & Human Services —
Previous trials (Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure [MERIT-HF], Cardiac Insufficiency Bisoprolol Study [CIBIS] II) have...