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Federal
Diagnostic and treatment characteristics of polycystic ovary syndrome: descriptive measurements of patient perception and awareness from 657 confidential self-reports
U.S. Department of Health & Human Services —
Background This investigation was undertaken to describe patient perception and awareness of the polycystic ovary syndrome (PCOS), the most common cause of... -
Federal
Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder
U.S. Department of Health & Human Services —
Idiopathic pulmonary fibrosis is a chronic and usually progressive lung disorder of unknown etiology. A growing body of evidence suggests that, in contrast to other... -
Federal
Asthma and PM
U.S. Department of Health & Human Services —
PM10 (the mass of particles present in the air having a 50% cutoff for particles with an aerodynamic diameter of 10 μm) is the standard measure of particulate air... -
Federal
Delayed union of femoral fractures in older rats:decreased gene expression
U.S. Department of Health & Human Services —
Background Fracture healing slows with age. While 6-week-old rats regain normal bone biomechanics at 4 weeks after fracture, one-year-old rats require more than 26... -
Federal
Severe community-acquired meningitis
U.S. Department of Health & Human Services —
Community-acquired meningitis is associated with high morbidity and mortality. The epidemiology of community-acquired meningitis has changed over the past 15 years... -
Federal
Oral sildenafil (Viagra™) in male erectile dysfunction: use, efficacy and safety profile in an unselected cohort presenting to a British district general hospital.
U.S. Department of Health & Human Services —
Introduction Sildenafil (Viagra®) is one of the drugs used in the first line therapy of male erectile dysfunction (MED). We have recorded outcomes, adverse events and... -
Federal
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
U.S. Department of Health & Human Services —
Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however... -
Federal
Appetite suppressants and valvular heart disease – a systematic review
U.S. Department of Health & Human Services —
Background Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain. Initial... -
Federal
MICE, a program to track and monitor animals in animal facilities
U.S. Department of Health & Human Services —
Background A growing number of laboratories are using the mouse as a model system in developmental biology as well as in molecular biology. Surprisingly, most of... -
Federal
Plasma colloid osmotic pressure in healthy infants
U.S. Department of Health & Human Services —
Background The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants... -
Federal
Antigen-specific cytometry
U.S. Department of Health & Human Services —
From its origins in the 16thcentury, microscopy has allowed the cell, as the basic unit of eukaryotic life and disease, to be identified and analyzed. Today,... -
Federal
Can Australian general practitioners effectively screen for diabetic retinopathy? A pilot study
U.S. Department of Health & Human Services —
Background Diabetes has been identified as one of the national health priority areas in Australia. After 20 years of diabetes most patients can be expected to develop... -
Federal
Debate: A subversive view of subsets - a dissident clinician's opinion
U.S. Department of Health & Human Services —
Clinical trialists and statisticians are very wary of subgroup analysis, for good reasons. Clinicians have to deal with situations in which subgroups of patients... -
Federal
Representation of women's health in general medical versus women's health specialty journals: a content analysis
U.S. Department of Health & Human Services —
Background Women's health, traditionally defined, emphasises reproductive and maternal conditions without consideration of social contexts. Advocates urge a broader... -
Federal
Use of antihypertensive medications in pregnancy and the risk of adverse perinatal outcomes: McMaster Outcome Study of Hypertension In Pregnancy 2 (
U.S. Department of Health & Human Services —
Background Uncertainty remains about the potential harmful effects of antihypertensive therapy on the developing fetus, especially for beta-blockers (βb). Methods We... -
Federal
Chronic obstructive pulmonary disease, asthma and protective effects of food intake: from hypothesis to evidence?
U.S. Department of Health & Human Services —
Evidence for a role of diet in asthma and chronic obstructive pulmonary disease (COPD) has been accumulating rapidly over the past decade. Associations have been... -
Federal
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology
U.S. Department of Health & Human Services —
Background An association between mumps-measles-rubella (MMR) vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to... -
Federal
Immune ablation and stem-cell therapy in autoimmune disease: Clinical experience
U.S. Department of Health & Human Services —
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an... -
Federal
Organization specific predictors of job satisfaction: findings from a Canadian multi-site quality of work life cross-sectional survey
U.S. Department of Health & Human Services —
Background Organizational features can affect how staff view their quality of work life. Determining staff perceptions about quality of work life is an important... -
Federal
Results of a phase-I/II randomized, masked, placebo-controlled trial of recombinant human interleukin-11 (rhIL-11) in the treatment of subjects with active rheumatoid arthritis
U.S. Department of Health & Human Services —
Interleukin-11 (IL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of...