96 datasets found
-
Federal
International Space Station conditions alter genomics proteomics and metabolomics in Aspergillus nidulans
National Aeronautics and Space Administration —
The first global genomic proteomic and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse kidney transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Multi-omic investigations of mouse liver subjected to simulated spaceflight freezing and storage protocols
National Aeronautics and Space Administration —
This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage... -
Federal
The development of Drosophila melanogaster during space flight
National Aeronautics and Space Administration —
In prospective human exploration of outer space the need to maintain a species over several generations under changed gravity conditions may arise. This paper reports... -
Federal
Impact of spaceflight on gene expression in the thymus
National Aeronautics and Space Administration —
The thymus undergoes atrophy during spaceflight. In this study we analyzed gene expression of the thymus of mice on board International space station to elucidate... -
Federal
Spatially resolved transcriptional analysis of brains from mice flown on the RR-3 mission
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Murine TCR-beta repertoire sequencing
National Aeronautics and Space Administration —
The purpose of this project was to determine the effects of chronic exposure to unpredictable mild socio-environmental stressors during gestation on the TCR-beta... -
Federal
Streptococcus mutans differential gene expression in response to simulated microgravity
National Aeronautics and Space Administration —
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host... -
Federal
During development the Sku5 mutant roots engage different genes than wild type WS roots either on the ground or in spaceflight.
National Aeronautics and Space Administration —
The wild type WS plants and the Sku5 mutant plants in the WS background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse gastrocnemius muscle transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
miRNA signature detection and countermeasures against HZE radiation exposure for tissue degeneration-Soleus muscle
National Aeronautics and Space Administration —
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA... -
Federal
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface Kirovograd region soil Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
National Aeronautics and Space Administration —
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These... -
Federal
Transcriptomic analysis of quadriceps from mice subjected to simulated spaceflight euthanasia freezing and tissue preservation protocols
National Aeronautics and Space Administration —
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression... -
Federal
A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells
National Aeronautics and Space Administration —
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the... -
Federal
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity
National Aeronautics and Space Administration —
Methods: RNA-seq libraries were prepared using the Illumina TruSeq RNA kit and the TrueSeq method was employed for mRNA enrichment. The libraries were quantified and...
96 datasets found