96 datasets found
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Federal
Temporal dynamics of the gut microbiota in people sharing a confined environment a 520-day ground-based space simulation MARS500
National Aeronautics and Space Administration —
The MARS500 project the longest ground-based space simulation ever provided us with a unique opportunity to trace the crew microbiota over 520 days of isolated... -
Federal
RNA-Seq transcriptome profiling of soleus from adult and aged mice following disuse muscle atrophy and recovery
National Aeronautics and Space Administration —
Rodent hind limb unloading was used as a model for reduced muscle activity and eventual atrophy. After a 10 day period of unloading mice in this study were xe2 x80... -
Federal
Adaptive changes in the vestibular system of land snail to a 30-day spaceflight and readaptation on return to Earth
National Aeronautics and Space Administration —
The vestibular system receives a permanent influence from gravity and reflexively controls equilibrium. If we assume gravity has remained constant during the species... -
Federal
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Murine TCR-beta repertoire sequencing
National Aeronautics and Space Administration —
The purpose of this project was to determine the effects of chronic exposure to unpredictable mild socio-environmental stressors during gestation on the TCR-beta... -
Federal
Multi-omic investigations of mouse liver subjected to simulated spaceflight freezing and storage protocols
National Aeronautics and Space Administration —
This study compares standard laboratory protocols for tissue freezing and storage with a simulation of the delayed processing of liver specimens and long-term storage... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse adrenal gland transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Transcriptomic analysis of liver from mice subjected to simulated spaceflight euthanasia freezing and tissue preservation protocols
National Aeronautics and Space Administration —
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse tibialis anterior muscle transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Deletion Collections Cultured during Spaceflight
National Aeronautics and Space Administration —
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle... -
Federal
Plasticity of the human IgM repertoire in response to a long-term spaceflight
National Aeronautics and Space Administration —
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are... -
Federal
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity
National Aeronautics and Space Administration —
Methods: RNA-seq libraries were prepared using the Illumina TruSeq RNA kit and the TrueSeq method was employed for mRNA enrichment. The libraries were quantified and... -
Federal
International Space Station flight project EXTREMOPHILES
National Aeronautics and Space Administration —
The International Space Station (ISS) is a unique habitat for humans and microorganisms. Here, we report the results of the ISS experiment EXTREMOPHILES, including... -
Federal
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface Kirovograd region soil Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
National Aeronautics and Space Administration —
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These... -
Federal
Comparative gene expression analysis in the Arabidopsis thaliana root apex using RNA-seq and microarray transcriptome profiles
National Aeronautics and Space Administration —
The root apex is an important section of the plant root involved in environmental sensing and cellular development. Analyzing the gene profile of root apex in diverse... -
Federal
Effect of microgravity on HUVECs (Human Umbilical vein Endothelial cells) cells and its transcriptome analysis.
National Aeronautics and Space Administration —
Adaptation of humans in low gravity conditions is a matter of utmost importance when efforts are on to a gigantic leap in human space expeditions for tourism and... -
Federal
RNA-Seq transcriptome analysis of reactive oxygen species gene network in Mizuna plants grown in long-term space flight
National Aeronautics and Space Administration —
Space environment is suspected to generate reactive oxygen species (ROS) and induce oxidative stress in plants however little is known about the gene expression of... -
Federal
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function
National Aeronautics and Space Administration —
With extended stays aboard the International Space Station (ISS) becoming commonplace there is a need to better understand the effects of microgravity on cardiac... -
Federal
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Mouse fecal microbiome after exposure to high LET radiation
National Aeronautics and Space Administration —
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose...
96 datasets found