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Federal
Differences in time of virus appearance in the blood and virus-specific immune responses in intravenous and intrarectal primary SIV
U.S. Department of Health & Human Services —
Background HIV-I can be transmitted by intravenous inoculation of contaminated blood or blood product or sexually through mucosal surfaces. Here we performed a pilot... -
Federal
Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals
U.S. Department of Health & Human Services —
Background Expression profiling holds great promise for rapid host genome functional analysis. It is plausible that host expression profiling in an infection could... -
Federal
B cells, BAFF/zTNF4, TACI, and systemic lupus erythematosus
U.S. Department of Health & Human Services —
B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the... -
Federal
Two pathways act in an additive rather than obligatorily synergistic fashion to induce systemic acquired resistance and
U.S. Department of Health & Human Services —
Background Local infection with necrotizing pathogens induces whole plant immunity to secondary challenge. Pathogenesis-related genes are induced in parallel with... -
Federal
The immunological effects of continuous veno-venous haemodiafiltration in critically ill patients
U.S. Department of Health & Human Services —
Background: Haemodynamic instability is common in septic patients with acute renal failure. Continuous veno-venous haemodiafiltration (CVVHD) is therefore used as an... -
Federal
Insights into rheumatoid arthritis derived from the Sa immune system
U.S. Department of Health & Human Services —
The Sa system is a recently described immune system that has a specificity and positive predictive value of nearly 100% for rheumatoid arthritis (RA) in Asia, Europe... -
Federal
Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value
U.S. Department of Health & Human Services —
The diagnosis of rheumatoid arthritis (RA) is primarily based on clinical symptoms, so it is often difficult to diagnose RA in very early stages of the disease. A... -
Federal
Immunodepression in the surgical patient and increased susceptibility to infection
U.S. Department of Health & Human Services —
Multiple organ failure is the major problem in intensive care patients. The failure of the organ 'immune system' is frequently overlooked, however. In this issue the... -
Federal
Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population
U.S. Department of Health & Human Services —
Background Vitamin D has been shown to exert manifold immunomodulatory effects. Type 1 diabetes mellitus (T1DM) is regarded to be immune-mediated and vitamin D... -
Federal
Where is biological therapy going?
U.S. Department of Health & Human Services —
The substantial progress in our understanding of molecular and cellular biology has allowed us to design biological therapeutics ('biologicals') with defined targets... -
Federal
A theoretical approach to predicting the success of genetic manipulation of malaria mosquitoes in malaria control
U.S. Department of Health & Human Services —
Background Mosquitoes that have been genetically modified to better encapsulate the malaria parasite Plasmodium falciparum are being considered as a possible tool in... -
Federal
Changes in cytokine production in healthy subjects practicing Guolin Qigong : a pilot study
U.S. Department of Health & Human Services —
Background Guolin Qigong is a combination of meditation, controlled breathing and physical movement designed to control the vital energy (qi) of the body and... -
Federal
Autoimmune response to U1 small nuclear ribonucleoprotein (U1 snRNP) associated with cytomegalovirus infection
U.S. Department of Health & Human Services —
The induction of autoantibodies to U1 small nuclear ribonucleoprotein (U1 snRNP) complexes is not well understood. We present evidence that healthy individuals with... -
Federal
Identifying research priorities on infections in older adults: proceedings of an interdisciplinary workshop
U.S. Department of Health & Human Services —
Background Infections pose a substantial burden to the health of older adults. In this report, we describe the proceedings of a workshop to formulate and prioritize... -
Federal
A case of central nervous system vasculitis related to an episode of Guillain-Barrè syndrome
U.S. Department of Health & Human Services —
The authors report their knowledge about an uncommon case of isolated vasculitis, restricted to the left sylvian artery during an auto-immune Guillain-Barrè syndrome... -
Federal
Catecholamine-induced interleukin-10 release: a key mechanism in systemic immunodepression after brain injury
U.S. Department of Health & Human Services —
Background: Infections after severe brain injury or polytrauma are still a problem, and may be the result of a brain-mediated disturbed systemic immunoreactivity. The... -
Federal
Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect - a histopathological and immunohistochemical study
U.S. Department of Health & Human Services —
Background Invasion and metastasis is a complex process governed by the interaction of genetically altered tumor cells and the immunological and inflammatory host... -
Federal
Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer
U.S. Department of Health & Human Services —
Background It is not uncommon to observe circulating tumor antigen-specific T lymphocytes in cancer patients despite a lack of significant infiltration and... -
Federal
Cell contact interactions in rheumatology, The Kennedy Institute for Rheumatology, London, UK, 1-2 June 2000
U.S. Department of Health & Human Services —
The intricate interactions that regulate relationships between endogenous tissue cells and infiltrating immune cells in the rheumatic joint, particularly in... -
Federal
Role of CD28/B7 costimulation and IL-12/IL-10 interaction in the radiation-induced immune changes
U.S. Department of Health & Human Services —
Background The present paper aims at studying the role of B7/CD28 interaction and related cytokine production in the immunological changes after exposure to different...