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Federal
Exercise training in heart failure
U.S. Department of Health & Human Services —
Chronic heart failure (CHF) is a common condition with a poor prognosis. It is associated with poor exercise tolerance and debilitating symptoms. These symptoms... -
Federal
Long-term experience with implanted intrathecal drug administration systems for failed back syndrome and chronic mechanical low back pain
U.S. Department of Health & Human Services —
Background Continuous intrathecal drug delivery has been shown in open studies to improve pain and quality of life in those with intractable back pain who have had... -
Federal
Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis
U.S. Department of Health & Human Services —
Purpose A systematic review of the literature was carried out to determine the role of prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC) .... -
Federal
Identification and preliminary characterization of mouse
U.S. Department of Health & Human Services —
Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely... -
Federal
Paper reports overview: The many guises of respiratory support, microalbuminuria and delirium
U.S. Department of Health & Human Services —
Paper reports overview: The many guises of respiratory support, microalbuminuria and delirium -
Federal
Alarms in the intensive care unit: how can the number of false alarms be reduced?
U.S. Department of Health & Human Services —
Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms.... -
Federal
Reduction of post injury neointima formation due to 17β-estradiol and phytoestrogen treatment is not influenced by the pure synthetic estrogen receptor antagonist ICI 182,780 in vitro
U.S. Department of Health & Human Services —
Background Animal and organ culture experiments have shown beneficial inhibitory estrogen effects on post injury neointima development. The purpose of this study was... -
Federal
NEAT: a domain duplicated in genes near the components of a putative Fe
U.S. Department of Health & Human Services —
Iron uptake from the host is essential for bacteria that infect animals. A protein domain has been identified that appears in variable copy number in bacterial genes... -
Federal
Separate urinary bladder and prostate neurons in the central nervous system of the rat: simultaneous labeling with two immunohistochemically distinguishable pseudorabies viruses
U.S. Department of Health & Human Services —
Background This work examines the central nervous system distribution of virus-labeled neurons from the rat urinary bladder and the prostate simultaneously within the... -
Federal
Chromosomal mapping, gene structure and characterization of the human and murine
U.S. Department of Health & Human Services —
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in... -
Federal
High calcium and dobutamine positive inotropy in the perfused mouse heart: myofilament calcium responsiveness, energetic economy, and effects of protein kinase C inhibition
U.S. Department of Health & Human Services —
Background In perfused hearts, high calcium-induced inotropy results in less developed pressure relative to myocardial oxygen consumption compared to the β-adrenergic... -
Federal
Cre reporter strains produced by targeted insertion of
U.S. Department of Health & Human Services —
Background Several Cre reporter strains of mice have been described, in which a lacZ gene is turned on in cells expressing Cre recombinase, as well as their daughter... -
Federal
Cytosolic acidification as a signal mediating hyperosmotic stress responses in
U.S. Department of Health & Human Services —
Background Dictyostelium cells exhibit an unusual response to hyperosmolarity that is distinct from the response in other organisms investigated: instead of... -
Federal
Mutant loxP vectors for selectable marker recycle and conditional knock-outs
U.S. Department of Health & Human Services —
Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40... -
Federal
Computational discovery of sense-antisense transcription in the human and mouse genomes
U.S. Department of Health & Human Services —
Overlapping but oppositely oriented transcripts have the potential to form sense-antisense perfect double-stranded (ds) RNA duplexes. A bioinformatics approach has... -
Federal
Normalization and analysis of DNA microarray data by self-consistency and local regression
U.S. Department of Health & Human Services —
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression... -
Federal
A possible alternative method for collecting mosquito larvae in rice fields
U.S. Department of Health & Human Services —
Background Rice fields are efficient breeding places for malaria vectors in Madagascar. In order to establish as easily as possible if a rice field is an effective... -
Federal
Four signature motifs define the first class of structurally related large coiled-coil proteins in plants.
U.S. Department of Health & Human Services —
Background Animal and yeast proteins containing long coiled-coil domains are involved in attaching other proteins to the large, solid-state components of the cell.... -
Federal
A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells
U.S. Department of Health & Human Services —
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked... -
Federal
Evidence for modulation of pericryptal sheath myofibroblasts in rat descending colon by Transforming Growth Factor β and Angiotensin II.
U.S. Department of Health & Human Services —
Background Absorption of water and Na+ in descending colonic crypts is dependent on the barrier function of the surrounding myofibroblastic pericryptal sheath. Here...