57 datasets found for "Elevation"
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Federal
Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice
U.S. Department of Health & Human Services —
Background Glaucoma is a common disease but its molecular etiology is poorly understood. It involves retinal ganglion cell death and optic nerve damage that is often... -
Federal
Arterial Wall Properties and Womersley Flow in Fabry Disease
U.S. Department of Health & Human Services —
Background Fabry disease is an X-linked recessive lysosomal storage disease resulting in the cellular accumulation of globotriaosylceramide particularly... -
Federal
Heat stress is associated with decreased lactic acidemia in rat sepsis
U.S. Department of Health & Human Services —
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in... -
Federal
Elevated antibody to D-alanyl lipoteichoic acid indicates caries experience associated with fluoride and gingival health
U.S. Department of Health & Human Services —
Background Acidogenic, acid-tolerant bacteria induce dental caries and require D-alanyl glycerol lipoteichoic acid (D-alanyl LTA) on their cell surface. Because... -
Federal
Anti-TNF-α antibody allows healing of joint damage in polyarthritic transgenic mice
U.S. Department of Health & Human Services —
Anti-tumor-necrosis-factor-α (TNF-α) monoclonal antibody was used to treat Tg197 transgenic mice, which constitutively produce human TNF-α (hTNF-α) and develop a... -
Federal
Implications of troponin testing in clinical medicine
U.S. Department of Health & Human Services —
During the past decade considerable research has been conducted into the use of cardiac troponins, their diagnostic capability and their potential to allow risk... -
Federal
Utility of the Mayo End-Stage Liver Disease (MELD) score in assessing prognosis of patients with alcoholic hepatitis
U.S. Department of Health & Human Services —
Background Alcoholic hepatitis is characterized by acute, or acute-on-chronic hepatic failure and associated with a high mortality. Specific therapies should be... -
Federal
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
U.S. Department of Health & Human Services —
Background Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many... -
Federal
Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis
U.S. Department of Health & Human Services —
BALB/c mice immunized with human cartilage proteoglycan (PG) develop arthritis accompanied by the production of autoantibodies to mouse cartilage PG. To determine... -
Federal
Ileal mucosal bile acid absorption is increased in Cftr knockout mice
U.S. Department of Health & Human Services —
Background Excessive loss of bile acids in stool has been reported in patients with cystic fibrosis. Some data suggest that a defect in mucosal bile acid transport... -
Federal
Omapatrilat normalizes renal function curve in spontaneously hypertensive rats
U.S. Department of Health & Human Services —
Background The present study was designed to analyze the chronic renal response to omapatrilat, a new vasopeptidase inhibitor, in spontaneously hypertensive rats... -
Federal
Predisposing factors for delirium in the surgical intensive care unit
U.S. Department of Health & Human Services —
Background Delirium is a sign of deterioration in the homeostasis and physical status of the patient. The objective of our study was to investigate the predisposing... -
Federal
Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor
U.S. Department of Health & Human Services —
Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of... -
Federal
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins
U.S. Department of Health & Human Services —
Background NGF exerts a variety of actions including promotion of neuronal differentiation and survival. The PC12 rat pheochromocytoma cell line has proved valuable... -
Federal
Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes.
U.S. Department of Health & Human Services —
Background Inhibitor of Apoptosis (IAP) proteins are key intrinsic regulators of apoptosis induced by a variety of triggers. We isolated the rat Inhibitor of... -
Federal
Drug-induced and postnatal hypothyroidism impairs the accumulation of diacylglycerol in liver and liver cell plasma membranes
U.S. Department of Health & Human Services —
Background Thyroid hormones are well known modulators of signal transduction. The effect of hyper- and hypo-thyroidism on diacylglycerol/protein kinase C (DAG/PKC)... -
Federal
Elevated calcitonin precursor levels are related to mortality in an animal model of sepsis
U.S. Department of Health & Human Services —
Background: Increased serum levels of procalcitonin (ProCT) and its component peptides have been reported in humans with sepsis. Using a hamster model of bacterial...
57 datasets found for "Elevation"