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Federal
Multi-exon deletions of the
U.S. Department of Health & Human Services —
Background Mutations in the fibrillin -1 gene (FBN1) cause Marfan syndrome (MFS), an autosomal dominant multi-system connective tissue disorder. The 200 different... -
Federal
Upregulation of the SERCA-type Ca
U.S. Department of Health & Human Services —
Background Ca2+-ATPases of endoplasmic reticulum (SERCAs) are responsible for maintenance of the micro- to millimolar Ca2+ ion concentrations within the endoplasmic... -
Federal
Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival
U.S. Department of Health & Human Services —
Background We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell... -
Federal
Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme
U.S. Department of Health & Human Services —
Background The tryptophan catabolizing enzyme, indoleamine 2,3, dioxygenase (IDO) is one of two mammalian enzymes, which can catabolize the rarest essential amino... -
Federal
Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p
U.S. Department of Health & Human Services —
Background SCF ubiquitin ligases share the core subunits cullin 1, SKP1, and HRT1/RBX1/ROC1, which associate with different F-box proteins. F-box proteins bind... -
Federal
Leukocyte adhesion and recruitment, and alpha-1-antitrypsin deficiency: a report from ATS 2001, May 18-23, San Francisco
U.S. Department of Health & Human Services —
The program at this year's American Thoracic Society international conference included over 300 scientific and clinical symposia. In this report I have reviewed the... -
Federal
Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5
U.S. Department of Health & Human Services —
Background The cyclic AMP specific phosphodiesterase, PDE4D5 interacts with the β-propeller protein RACK1 to form a signaling scaffold complex in cells. Two-hybrid... -
Federal
Cellophane based mini-prep method for DNA extraction from the filamentous fungus
U.S. Department of Health & Human Services —
Background Methods for the extraction of DNA from filamentous fungi are frequently laborious and time consuming because most of the available protocols include... -
Federal
Cellular responses to
U.S. Department of Health & Human Services —
Background Plasmodium falciparum erythrocyte membrane protein-1, a variant antigen of the malaria parasite, is potentially a target for the immune response. It would... -
Federal
Re-HEDP : pharmacokinetic characterization, clinical and dosimetric evaluation in osseous metastatic patients with two levels of radiopharmaceutical dose
U.S. Department of Health & Human Services —
Background A study for pain relief therapy with 188Re-HEDP was done in patients with bone metastases secondary to breast and prostate cancer. Materials and Methods... -
Federal
Quantitation of the distribution and flux of myosin-II during cytokinesis
U.S. Department of Health & Human Services —
Background During cytokinesis, the cell's equator contracts against the cell's global stiffness. Identifying the biochemical basis for these mechanical parameters is... -
Federal
Volumetric computerized tomography as a measurement of periprosthetic acetabular osteolysis and its correlation with wear
U.S. Department of Health & Human Services —
Osteolysis, which is considered to be a major source of morbidity following total hip joint replacement, has been notoriously difficult to measure accurately,... -
Federal
Chromosomal aberrations in benign and malignant Bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
U.S. Department of Health & Human Services —
Background Bilharzia-associated bladder cancer (BAC) is a major health problem in countries where urinary schistosomiasis is endemic. Characterization of the genetic...