124 datasets found
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Federal
Synergistic effects of microgravity and space radiation (Nimblegen)
National Aeronautics and Space Administration —
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still... -
Federal
Streptococcus mutans differential gene expression in response to simulated microgravity
National Aeronautics and Space Administration —
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host... -
Federal
Whole Metagenome Profiles of Particulates Collected from the International Space Station
National Aeronautics and Space Administration —
The microbial composition of the International Space Station (ISS) environment is of critical interest due to potential impact of its constituents on human health and... -
Federal
Impact of Antiorthostatic Suspension on Mouse response to Tetanus Toxoid and CpG
National Aeronautics and Space Administration —
These data were generated from mice that were skeletally unloaded using antiorthostatic suspension (AOS). Mice were either subjected to AOS or tail restraint without... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse adrenal gland transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
The influence of simulated microgravity on the proteome of Daphnia magna
National Aeronautics and Space Administration —
Background/Objectives: The waterflea Daphnia is an interesting candidate for bioregenerative life support systems (BLSS). These animals are particularly promising... -
Federal
Global gene expression analysis highlights microgravity sensitive key genes in soleus and EDL of 30 days space flown mice
National Aeronautics and Space Administration —
Microgravity exposure as well as chronic muscle disuse are two of the main causes of physiological adaptive skeletal muscle atrophy in humans and murine animals in... -
Federal
Transcriptomic analysis of liver from mice subjected to simulated spaceflight euthanasia freezing and tissue preservation protocols
National Aeronautics and Space Administration —
To understand the molecular mechanisms affected by spaceflight it is essential to achieve high quality sample preservation on-orbit for downstream gene expression... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Federal
During development the Sku5 mutant roots engage different genes than wild type WS roots either on the ground or in spaceflight.
National Aeronautics and Space Administration —
The wild type WS plants and the Sku5 mutant plants in the WS background were germinated on ISS or on the ground and the gene expression profiles in roots at 4 days or... -
Federal
Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface Kirovograd region soil Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone
National Aeronautics and Space Administration —
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These... -
Federal
Streptococcus mutans differential gene expression in response to simulated microgravity
National Aeronautics and Space Administration —
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host... -
Federal
Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Deletion Collections Cultured during Spaceflight
National Aeronautics and Space Administration —
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle... -
Federal
Galactic cosmic radiation induces stable epigenome alterations relevant to human lung cancer
National Aeronautics and Space Administration —
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in... -
Federal
Effects of 21 days of bedrest on human skeletal muscle gene expression
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic... -
Federal
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Analysis of dust samples from the Russian part of the ISS
National Aeronautics and Space Administration —
Our study focuses on the hardiest microorganisms inhabiting the ISS in order to assess their diversity and capabilities to resist certain stresses. We specifically... -
Federal
Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA DNA and protein were purified... -
Federal
Microbial monitoring in the ISS-Kibo
National Aeronautics and Space Administration —
Continuous monitoring of bacterial community structure in the ISS-Kibo. This data contains numerous sequence reads of 16S rRNA gene fragments.
124 datasets found