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Federal
Low dose (0.04 Gy) irradiation (LDR) and hindlimb unloading (HLU) microgravity in mice: retina transcriptomic and epigenomic data recent views
National Aeronautics and Space Administration —
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose... -
Federal
Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes recent views
National Aeronautics and Space Administration —
We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene... -
Federal
Reproducible changes in gut microbiome reveal a shift in microbial and host metabolism during spaceflight recent views
National Aeronautics and Space Administration —
Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-... -
Federal
Microbial Observatory (ISS-MO): Study of BSL-2 bacterial isolates from the International Space Station recent views
National Aeronautics and Space Administration —
In an on-going Microbial Observatory experimental investigation on the International Space Station (ISS) multiple bacterial isolates of Biosafety Level 2 (BSL-2) were... -
Federal
Quantitative evaluation of bioaerosols in different particle size fractions collected on the International Space Station (ISS) recent views
National Aeronautics and Space Administration —
Exposure to bioaerosols can negatively impact human health. On the International Space Station (ISS) this exposure differs to that on Earth due to lack of... -
Federal
Whole genome sequencing and assembly of Eukaryotic microbes isolated from ISS environmental surface Kirovograd region soil Chernobyl Nuclear Power Plant and Chernobyl Exclusion Zone recent views
National Aeronautics and Space Administration —
The whole-genome sequences of eight fungal strains that were selected for exposure to microgravity at the International Space Station are presented here. These... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse soleus muscle transcriptomic and epigenomic data recent views
National Aeronautics and Space Administration —
NASA s Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Arg1 functions in the physiological adaptation of undifferentiated plant cells to spaceflight recent views
National Aeronautics and Space Administration —
In this study transcriptome profiling was used to gain insight into the spaceflight adaptation role of Altered response to gravity-1 (Arg1) a gene known to affect... -
Federal
Metagenomic analysis of feces from mice flown on the RR-9 mission recent views
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Microgravity effect on C. elegans N2/VC (CERISE 4 days) recent views
National Aeronautics and Space Administration —
Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 4 days in the Japanese... -
Federal
Spaceflight effects on the mouse retina: Histological gene expression and epigenetic changes after flight on STS-135 recent views
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Microbial Observatory (ISS-MO): Antimicrobial resistance genes recent views
National Aeronautics and Space Administration —
The environmental samples were collected with the polyester wipes from eight different locations in the International Space Station (ISS) during two consecutive... -
Federal
Microbial monitoring in the ISS-Kibo recent views
National Aeronautics and Space Administration —
Continuous monitoring of bacterial community structure in the ISS-Kibo. This data contains numerous sequence reads of 16S rRNA gene fragments. -
Federal
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant cytoskeleton in microgravity with gene profiling and cytochemistry recent views
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Microbial Observatory (ISS-MO): Molecular characterization of Bacillus issensis sp. nov. isolated from various quarters of the International Space Station recent views
National Aeronautics and Space Administration —
As part of an ongoing effort to catalogue microbial communities inhabiting the International Space Station (ISS) crew-associated environmental samples were collected... -
Federal
RNA-seq analysis of mycobacteria stress response to microgravity recent views
National Aeronautics and Space Administration —
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M.... -
Federal
Mouse femur LC-MSMS upon weightlessness recent views
National Aeronautics and Space Administration —
Bone loss and immune dysregulation are among the main adverse outcomes of spaceflight challenging astronaut xe2 x80 x99s health and safety. However consequences on B... -
Federal
Evaluation of in vitro macrophage differentiation during space flight recent views
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Age and Space Irradiation Modulate Tumor Progression: Implications for Carcinogenesis Risk recent views
National Aeronautics and Space Administration —
Age plays a major role in tumor incidence and is an important consideration when modeling the carcinogenesis process or estimating cancer risks. Epidemiological data... -
Federal
Response to Low Shear Modeled Microgravity Indicates Translation of Lactobacillus acidophilus ATCC 4356 Benefits to Spaceflight recent views
National Aeronautics and Space Administration —
The introduction of generally recognized as safe (GRAS) probiotic microbes into the spaceflight food system has the potential for use as a safe non-invasive daily...