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Federal
Rapid Experimental Estimates of Physicochemical Properties
U.S. Environmental Protection Agency —
We have performed high-throughput experimental estimates of five physicochemical properties for a set of 200 chemicals to evaluate the consistency with previous... -
Federal
Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells
U.S. Environmental Protection Agency —
In zebrafish, 161 compounds were screened and 34 were identified by visual inspection as VDCs, of which 28 were confirmed as VDCs by quantitative image analysis.... -
Federal
Development of a Flame Retardant and an Organohalogen Flame Retardant Chemical Inventory
U.S. Environmental Protection Agency —
This dataset is the result of a joint EPA-CPSC effort to catalogue flame retardant (and more specifically organohalogen flame retardant chemicals). Full details of... -
Federal
Predictive Structure-Based Toxicology Approaches To Assess the Androgenic Potential of Chemicals
U.S. Environmental Protection Agency —
Chemical structures, RMSD values, docking scores, additional tables and figures, and methodological details (PDF) Additional information concerning the starting data... -
Federal
The chemical landscape of high-throughput new approach methodologies for exposure
U.S. Environmental Protection Agency —
Data for the publication Isaacs, K.K., Egeghy, P., Dionisio, K.L. et al. The chemical landscape of high-throughput new approach methodologies for exposure. J Expo Sci... -
Federal
A geospatial modeling approach to quantifying the risk of exposure to environmental chemical mixtures via a common molecular target
U.S. Environmental Protection Agency —
Data files for "Eccles KM, Karmaus AL, Kleinstreuer NC, Parham F, Rider CV, Wambaugh JF, Messier KP. A geospatial modeling approach to quantifying the risk of... -
Federal
Datasets for PUC paper 09182018
U.S. Environmental Protection Agency —
Datasets associated with the publication "Establishing a System of Consumer Products Categories to Support Rapid Modeling of Human Exposure". This dataset is... -
Federal
Honda_Wambaugh_Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions
U.S. Environmental Protection Agency —
All relevant data are within the manuscript, its Supporting Information files, and the httk R software package v1.9.2. This dataset is associated with the following... -
Federal
Confirmation of High-Throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays
U.S. Environmental Protection Agency —
All data is generated by the external authors or taken from public data sources. This dataset is not publicly accessible because: Data was not collected in EPA labs... -
Federal
Data for Turley et al. "Applying the RISK21 approach to assess predictivity of new approach methodologies..."
U.S. Environmental Protection Agency —
Data for publication Turley et al. "Applying the RISK21 approach to assess predictivity of new approach methodologies in toxicity testing and exposure assessment: a... -
Federal
No data
U.S. Environmental Protection Agency —
Manuscript provides a look-up table to predict exposures from minimal information using ECETOC TRA software. This dataset is not publicly accessible because: There is... -
Federal
(Crit. Rev. Tox.) Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects
U.S. Environmental Protection Agency —
This paper uses EPA public data to build new datasets and analysis by non-EPA authors. This dataset is not publicly accessible because: Data was not collected in EPA... -
Federal
(Crit. Rev. Tox.) Comparing rat and rabbit embryo-fetal developmental toxicity studies for 379 pharmaceuticals: On systemic dose and developmental effects
U.S. Environmental Protection Agency —
A database of embryo-fetal developmental toxicity (EFDT) studies of 379 pharmaceutical compounds in rat and rabbit. This dataset is not publicly accessible because:... -
Federal
HTTK R Package v1.7 - Evaluation and Calibration of High-Throughput Predictions of Chemical Distribution to Tissues
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion
U.S. Environmental Protection Agency —
Paper studying synthetic hydrogels as an alternative to matrigel. This dataset is not publicly accessible because: Research data consisted of secondary data only. It... -
Federal
Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system
U.S. Environmental Protection Agency —
The ToxCast program has generated in vitro screening data on over a thousand chemicals to assess potential disruption of important biological processes and assist in... -
Federal
(Archives of Toxicology) Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment
U.S. Environmental Protection Agency —
To determine the best way to select predictive groups of genes, we used published microarray data from dose-response studies on six chemicals in rats exposed orally... -
Federal
Quantitative Structure-Use Relationship Model Predictions to evaluate Tox21 Chemicals as Functional Substitutes and Candidate Alternatives
U.S. Environmental Protection Agency —
This dataset provides a prediction for all Tox21 chemicals with available QSUR descriptors across all 41 valid QSUR models developed with FUse. This dataset is... -
Federal
Quantitative Structure-Use Relationship Model thresholds for Model Validation, Domain of Applicability, and Candidate Alternative Selection
U.S. Environmental Protection Agency —
This file contains value of the model training set confusion matrix, domain of applicability evaluation based on training set to predicted chemicals structural...