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Federal
Alterations of E-cadherin and β-catenin in gastric cancer
U.S. Department of Health & Human Services —
Background The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the... -
Federal
Abdominal compartment syndrome
U.S. Department of Health & Human Services —
Abdominal compartment syndrome -
Federal
The diagnostic value of liver biopsy
U.S. Department of Health & Human Services —
Background Since the introduction of molecular diagnostic tools such as markers for hepatitis C and different autoimmune diseases, liver biopsy is thought to be... -
Federal
Linkage analysis of HLA and candidate genes for celiac disease in a North American family-based study
U.S. Department of Health & Human Services —
Background Celiac disease has a strong genetic association with HLA. However, this association only explains approximately half of the sibling risk for celiac... -
Federal
Problems in dealing with missing data and informative censoring in clinical trials
U.S. Department of Health & Human Services —
A common problem in clinical trials is the missing data that occurs when patients do not complete the study and drop out without further measurements. Missing data... -
Federal
The International Sepsis Forum's controversies in sepsis: how will sepsis be treated in 2051?
U.S. Department of Health & Human Services —
Great advances have been made in describing the intracellular pathways and genes that are activated by bacterial products. New definitions and therapies for sepsis... -
Federal
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol
U.S. Department of Health & Human Services —
Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket.... -
Federal
Continuous haemofiltration in the intensive care unit
U.S. Department of Health & Human Services —
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU).... -
Federal
Impact of false-positive mammography on subsequent screening attendance and risk of cancer
U.S. Department of Health & Human Services —
Background One area of concern within the largely successful UK National Health Service breast screening programme is the relatively high proportion of women showing... -
Federal
The genetics of rheumatoid arthritis and the need for animal models to find and understand the underlying genes
U.S. Department of Health & Human Services —
The causes of rheumatoid arthritis (RA) are largely unknown. However, RA is most probably a multifactorial disease with contributions from genetic and environmental... -
Federal
Weather conditions and sudden sensorineural hearing loss
U.S. Department of Health & Human Services —
Background Climatic or meteorological condition changes have been implicated in the pathogenesis of Idiopathic Sudden Sensorineural Hearing Loss (ISSHL). We... -
Federal
Use of intravenous antiarrhythmics to identify concealed Brugada syndrome
U.S. Department of Health & Human Services —
Cardiology has recently witnessed the production of an overwhelming amount of data through the advances made in genetics and molecular biology research. Understanding... -
Federal
Long term benzodiazepine use for insomnia in patients over the age of 60: discordance of patient and physician perceptions
U.S. Department of Health & Human Services —
Background The aim of this study was to determine and compare patients' and physicians' perceptions of benefits and risks of long term benzodiazepine use for insomnia... -
Federal
Inhibition of spontaneous induction of lambdoid prophages in
U.S. Department of Health & Human Services —
Background Infections of bacterial cultures by bacteriophages are serious problems in biotechnological laboratories. Apart from such infections, prophage induction in... -
Federal
Genetic polymorphisms in lung disease: bandwagon or breakthrough?
U.S. Department of Health & Human Services —
The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to... -
Federal
Prevalence of attention deficit/hyperactivity disorder among adults in obesity treatment
U.S. Department of Health & Human Services —
Background Bariatric patients showing poor "focus" during treatment more often failed to lose weight or maintain reduced weight. Evaluation of these patients... -
Federal
Antenatal screening and its possible meaning from unborn baby's perspective
U.S. Department of Health & Human Services —
In recent decades antenatal screening has become one of the most routine procedure of pregnancy-follow up and the subject of hot debate in bioethics circles. In this... -
Federal
Food intakes and preferences of hospitalised geriatric patients
U.S. Department of Health & Human Services —
Background A cross sectional survey was carried out on 120 hospitalised geriatric patients aged 60 and above in Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur... -
Federal
Practising evidence-based medicine: the design and implementation of a multidisciplinary team-driven extubation protocol
U.S. Department of Health & Human Services —
Background Evidence from recent literature shows that protocol-directed extubation is a useful approach to liberate patients from mechanical ventilation (MV).... -
Federal
Genetic determinants of mammographic density
U.S. Department of Health & Human Services —
Background Changes in breast density are highly correlated with steroid hormone exposure. Materials and methods In a cross-sectional study of 396 Caucasian and...