288 datasets found
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Federal
Effects of low dose space radiation exposures on the splenic metabolome
National Aeronautics and Space Administration —
Future space missions will include return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Flow Cytometry, Blood)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
Effects of spaceflight on murine skeletal muscle gene expression
National Aeronautics and Space Administration —
Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts towards faster muscle fiber types. To identify changes in gene... -
Federal
The effect of spaceflight on transgenic Arabidopsis plants with compromised signaling
National Aeronautics and Space Administration —
Understanding the molecular mechanisms by which plants sense and adapt to changes in the space environment is essential for generating plants that are better adapted... -
Federal
Immediate Transcriptional Changes in Response to High Dose Radiation Exposure
National Aeronautics and Space Administration —
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars.... -
Federal
Proteomics and Transcriptomics analysis of Arabidopsis Seedlings in Microgravity
National Aeronautics and Space Administration —
On Earth plants are constantly exposed to a gravitational field of 1G. Gravity affects a plant in every step of its development. Germinating seedlings orient their... -
Federal
Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight.
National Aeronautics and Space Administration —
Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle... -
Federal
SpaceX Inspiration4 Dragon Capsule Metagenomic and Metatranscriptomic Microbial Swabs
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
Transcriptional profiling of roots and shoots from Brachypodium distachyon seedlings flown on the ISS
National Aeronautics and Space Administration —
Most major cereal grain crops are monocots. Yet, most investigations of plant adaptation to the spaceflight environment have been carried out on the dicotyledonous... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse extensor digitorum longus muscle transcriptomic and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Transcriptional analysis of liver from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Effects of 5-ion 6-beam sequential irradiation in the presence and absence of hindlimb or control hindlimb unloading on behavioral performances and plasma metabolic pathways of Fischer 344 rats
National Aeronautics and Space Administration —
Effects and interactions between different spaceflight stressors are expected to be experienced by crew on missions when exposed to microgravity and galactic cosmic... -
Federal
Microbial Observatory (ISS-MO): Molecular characterization of Bacillus issensis, sp. nov., isolated from various quarters of the International Space Station
National Aeronautics and Space Administration —
As part of an ongoing effort to catalogue microbial communities inhabiting the International Space Station (ISS) crew-associated environmental samples were collected... -
Federal
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats (Estrous Cycle Monitoring)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Characterization of Biofilm Formation, Growth, and Gene Expression on Different Materials and Environmental Conditions in Microgravity (Morphology of Pseudomonas aeruginosa biofilms)
National Aeronautics and Space Administration —
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance,... -
Federal
CI Asteroid Regolith as an In Situ Plant Growth Medium for Space Crop Production
National Aeronautics and Space Administration —
Human expansion into the solar system is currently at the forefront of space research. For our astronauts to survive, they will need to be fed a healthy and... -
Federal
Microgravity effects on leaf morphology, cell structure, carbon metabolism and mRNA expression of dwarf wheat
National Aeronautics and Space Administration —
The PESTO experiment was launched on April 8, 2002 onboard STS-110 (Atlantis) and was returned on June 19, 2002 onboard STS-111 (Endeavor), a total of 73 days in... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of hippocampi from mice flown on the RRRM-2 mission
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
International Space Station conditions alter genomics, proteomics, and metabolomics in Aspergillus nidulans
National Aeronautics and Space Administration —
The first global genomic, proteomic, and secondary metabolomic characterization of the filamentous fungus Aspergillus nidulans following growth onboard the...
288 datasets found