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Federal
Biological Research in Canisters-16 (BRIC-16): Investigations of the plant cytoskeleton in microgravity with gene profiling and cytochemistry recent views
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Gene-expression profiling of Saccharomyces cerevisiae irradiated by high-LET radiations recent views
National Aeronautics and Space Administration —
Ionizing radiations are categorized by linear energy transfer (LET) into low-LET and high-LET. High-LET is considered to have a higher relative biological... -
Federal
MicroRNA expression of C. elegans in space environment recent views
National Aeronautics and Space Administration —
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam recent views
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Response of human lymphoblastoid cells to activated medium recent views
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in... -
Federal
Effects of 21 days of bedrest on human skeletal muscle gene expression recent views
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) on skeletal muscle gene expression. 14 male subjects participated in normoxic... -
Federal
Transcription profiling of Drosophila exposed to a levitation magnet for different lengths of time recent views
National Aeronautics and Space Administration —
Drosophila samples were exposed to the levitation magnet inside a 25mm diameter tubes with 3 ml of yeast-based Drosophila food in the bottom and a chamber of only 5... -
Federal
Evaluation of in vitro macrophage differentiation during space flight recent views
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Spaceflight effects on the mouse retina: Histological gene expression and epigenetic changes after flight on STS-135 recent views
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Expression data from SPHINX (SPaceflight of Huvec: an INtegrated eXperiment) recent views
National Aeronautics and Space Administration —
Changes in the physical environment modulate cell responses and may lead to the impairment or even failure of tissue function as a result of mechanotransduction... -
Federal
Woman skeletal muscle transcriptome with bed rest and countermeasures. recent views
National Aeronautics and Space Administration —
Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading... -
Federal
Gene responses in mouse brain to long-term exposure to microgravity recent views
National Aeronautics and Space Administration —
The spaceflight experiment was carried out using male C57BL/10J mice (8 weeks old at launch). Wild type mice (n=3) were launched by Space Shuttle Discovery and housed... -
Federal
Gene responses in mouse brain to long-term exposure to microgravity recent views
National Aeronautics and Space Administration —
The spaceflight experiment was carried out using male C57BL/10J mice (8 weeks old at launch). Wild type mice (n=3) were launched by Space Shuttle Discovery and housed... -
Federal
mRNA expression profile in DLD-1 and MOLT-4 cancer cell lines cultured under Microgravity recent views
National Aeronautics and Space Administration —
DLD-1 and MOLT-4 cell lines were cultured in a rotating cell culture system to simulate microgravity and mRNA expression profile in comparison to Static controls.... -
Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator recent views
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment recent views
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells... -
Federal
MESSAGE 2 space experiment with Rhodospirillum rubrum S1H recent views
National Aeronautics and Space Administration —
R. rubrum S1H inoculated on solid agar rich media was sent to the ISS in October 2003 (MESSAGE-part 2 experiment). After 10 days flight R. rubrum cultures returned... -
Federal
Effect of acute muscle unloading on soleus and gastrocnemius muscle gene expression recent views
National Aeronautics and Space Administration —
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of... -
Federal
Global DNA methylation profiling of radiation-induced rat mammary carcinomas recent views
National Aeronautics and Space Administration —
To investigate DNA methylation patterns in rat mammary carcinomas induced by ionizing radiation. DNA methylation patterns were analyzed in radiation-induced rat... -
Federal
BRIC-23 GeneLab Process Verification Test: Bacillus subtilis transcriptomic proteomic and metabolomic data recent views
National Aeronautics and Space Administration —
Microbes interact with humans in complex ways and understanding how they respond to the spaceflight environment is important to the success of future manned...