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Federal
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
U.S. Department of Health & Human Services —
Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however... -
Federal
Penis size: Survey of female perceptions of sexual satisfaction
U.S. Department of Health & Human Services —
Background Does the size of the male penis, in terms of length or width, make a difference in female sexual satisfaction? Method To study the effect of penis width... -
Federal
Appetite suppressants and valvular heart disease – a systematic review
U.S. Department of Health & Human Services —
Background Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain. Initial... -
Federal
The current status of primary prevention in coronary heart disease
U.S. Department of Health & Human Services —
During the second part of the twentieth century, research advances caused a substantial decline in the rate of coronary heart disease. The decline lasted from the... -
Federal
A comparison of volume control and pressure-regulated volume control ventilation in acute respiratory failure
U.S. Department of Health & Human Services —
Background: The aim of this study was to test the hypothesis that a new mode of ventilation (pressure-regulated volume control; PRVC) is associated with improvements... -
Federal
Can Australian general practitioners effectively screen for diabetic retinopathy? A pilot study
U.S. Department of Health & Human Services —
Background Diabetes has been identified as one of the national health priority areas in Australia. After 20 years of diabetes most patients can be expected to develop... -
Federal
Systematic reviews of complementary therapies - an annotated bibliography. Part 1: Acupuncture
U.S. Department of Health & Human Services —
Background Complementary therapies are widespread but controversial. We aim to provide a comprehensive collection and a summary of systematic reviews of clinical... -
Federal
Immune ablation and stem-cell therapy in autoimmune disease: Clinical experience
U.S. Department of Health & Human Services —
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an... -
Federal
What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ?
U.S. Department of Health & Human Services —
At times of crisis when epidemics rage and begin to take their toll on affected populations, as we have been witnessing with African trypanosomiasis in subSahara, the... -
Federal
Journal of Biomedicine and Biotechnology
U.S. Department of Health & Human Services —
Journal of Biomedicine and Biotechnology -
Federal
Pooling, meta-analysis, and the evaluation of drug safety
U.S. Department of Health & Human Services —
Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a... -
Federal
Drug-induced and postnatal hypothyroidism impairs the accumulation of diacylglycerol in liver and liver cell plasma membranes
U.S. Department of Health & Human Services —
Background Thyroid hormones are well known modulators of signal transduction. The effect of hyper- and hypo-thyroidism on diacylglycerol/protein kinase C (DAG/PKC)... -
Federal
Retrovirus-delivered siRNA
U.S. Department of Health & Human Services —
The ability of transfected synthetic small interfering (si) RNAs to suppress the expression of specific transcripts has proved a useful technique to probe gene... -
Federal
Insertion of a small peptide of six amino acids into the β7–β8 loop of the p51 subunit of HIV-1 reverse transcriptase perturbs the heterodimer and affects its activities
U.S. Department of Health & Human Services —
Background HIV-1 RT is a heterodimeric enzyme, comprising of the p66 and p51 subunits. Earlier, we have shown that the β7-β8 loop of p51 is a key structural element... -
Federal
Impaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40)
U.S. Department of Health & Human Services —
Background SPARC is a matricellular protein involved in cell-matrix interactions. From expression patterns at the wound site and in vitro studies, SPARC has been... -
Federal
Impact of nosocomial pneumonia on the outcome of mechanically-ventilated patients
U.S. Department of Health & Human Services —
Background: Nosocomial pneumonia (NP) is a common complication in mechanically-ventilated patients and is considered to be one of the most common causes of morbidity... -
Federal
Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.
U.S. Department of Health & Human Services —
Background Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of... -
Federal
Long termin-vivostudies of a photo-oxidized bovine osteochondral transplant in sheep
U.S. Department of Health & Human Services —
Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been... -
Federal
Astroglial expression of the P-glycoprotein is controlled by intracellular CNTF
U.S. Department of Health & Human Services —
Background The P-glycoprotein (P-gp), an ATP binding cassette transmembrane transporter, is expressed by astrocytes in the adult brain, and is positively modulated... -
Federal
Genomic comparisons among
U.S. Department of Health & Human Services —
Background Insertion Sequence (IS) elements are mobile genetic elements widely distributed among bacteria. Their activities cause mutations, promoting genetic...