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Federal
PFAS PBPK Template Model
U.S. Environmental Protection Agency —
The data set includes source code that implements a PBPK template model applicable to PFAS. It includes data digitized from Kim et al. (2018), Kim et al. (2019), and... -
Federal
Vapor uptake inhalation data for chloroform in F344 rats
U.S. Environmental Protection Agency —
This dataset describes disappearance of chloroform from a vapor uptake chamber with time due to metabolism. The research concentrates on optimization for estimation... -
Federal
Naphthalene PBPK Model with Inhalation and Skin Routes of Exposure
U.S. Environmental Protection Agency —
This data set includes source code that implements a PBPK model for naphthalene that allows for inhalation and skin routes of exposure. It also includes data... -
Federal
High-throughput in-silico prediction of ionization equilibria for pharmacokinetic modeling
U.S. Environmental Protection Agency —
Estimates of ionization equilibrium constants (i.e., pKa) were analyzed for 8,132 pharmaceuticals and 24,281 other compounds to which humans might be exposed in the... -
Federal
The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM)
U.S. Environmental Protection Agency —
This dataset contains model code and supporting analysis files necessary to evaluate the impact of variability in human hepatic scaling factors. Variation in scaling...