Vapor uptake inhalation data for chloroform in F344 rats
This dataset describes disappearance of chloroform from a vapor uptake chamber with time due to metabolism. The research concentrates on optimization for estimation of metabolic constants using a novel technique.
This dataset is associated with the following publication:
Evans, M., C. Eklund, D. williams, Y. Sey, and J. Simmons. Global Optimization of the Michaelis-Menten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 32(3): 97-109, (2020).
Resources
1 resource available
-
EvansMarina_A-z35r_20190702.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
Find Related Datasets
Search by Tags
Click any tag below to search for similar datasets
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Marina Evans", "hasEmail": "mailto:evans.marina@epa.gov" } |
| description | This dataset describes disappearance of chloroform from a vapor uptake chamber with time due to metabolism. The research concentrates on optimization for estimation of metabolic constants using a novel technique. This dataset is associated with the following publication: Evans, M., C. Eklund, D. williams, Y. Sey, and J. Simmons. Global Optimization of the Michaelis-Menten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 32(3): 97-109, (2020). |
| distribution |
[ { "title": "EvansMarina_A-z35r_20190702.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504242/EvansMarina_A-z35r_20190702.xlsx" } ] |
| identifier | https://doi.org/10.23719/1504242 |
| keyword |
[ "Chloroform", "PBPK model", "vapor uptake inhalation" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-07-02 |
| programCode |
[ "020:096" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1080/08958378.2020.1742818" ] |
| rights |
null
|
| title | Vapor uptake inhalation data for chloroform in F344 rats |
