{
  "accessLevel": "public",
  "bureauCode": [
    "020:00"
  ],
  "contactPoint": {
    "fn": "Marina Evans",
    "hasEmail": "mailto:evans.marina@epa.gov"
  },
  "description": "This dataset describes disappearance of chloroform from a vapor uptake chamber with time due to metabolism. The research concentrates on optimization for estimation of metabolic constants using a novel technique. \n\nThis dataset is associated with the following publication:\nEvans, M., C. Eklund, D. williams, Y. Sey, and J. Simmons. Global Optimization of the Michaelis-Menten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats.   INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 32(3): 97-109, (2020).",
  "distribution": [
    {
      "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504242/EvansMarina_A-z35r_20190702.xlsx",
      "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
      "title": "EvansMarina_A-z35r_20190702.xlsx"
    }
  ],
  "identifier": "https://doi.org/10.23719/1504242",
  "keyword": [
    "Chloroform",
    "PBPK model",
    "vapor uptake inhalation"
  ],
  "license": "https://pasteur.epa.gov/license/sciencehub-license.html",
  "modified": "2019-07-02",
  "programCode": [
    "020:096"
  ],
  "publisher": {
    "name": "U.S. EPA Office of Research and Development (ORD)",
    "subOrganizationOf": {
      "name": "U.S. Environmental Protection Agency",
      "subOrganizationOf": {
        "name": "U.S. Government"
      }
    }
  },
  "references": [
    "https://doi.org/10.1080/08958378.2020.1742818"
  ],
  "rights": null,
  "title": "Vapor uptake inhalation data for chloroform in F344 rats"
}