32 datasets found
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Federal
Genetic Dissection of the Spaceflight Transcriptome Responses in Plants: are some responses unnecessary?
National Aeronautics and Space Administration —
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural... -
Federal
Dynamic gene expression response to altered gravity in human myelomonocytic U937 cells [parabolic]
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to... -
Federal
Efficient Identification of Multiple Pathways: RNA-Seq Analysis of Livers from 56Fe Ion Irradiated Mice
National Aeronautics and Space Administration —
Background: mRNA interactions with each other and other signaling molecules define different biological pathways and functions. Researchers have been investigating... -
Federal
Immune responses to the in vitro LPS assault engineered in the spaceflight multi-omics study
National Aeronautics and Space Administration —
Microgravity alters the immune response to in vitro LPS assault engineered in spaceflight: A multi-omics study Microgravity can facilitate creation of a potent... -
Federal
Alteration of Proteomes in First-generation Cultures of Bacillus pumilus Spores Exposed to Outer Space
National Aeronautics and Space Administration —
Bacillus pumilus SAFR-032 was originally isolated from the Jet Propulsion Lab Spacecraft Assembly Facility and thoroughly characterized for its enhanced resistance to... -
Federal
Dynamic gene expression response to altered gravity in human myelomonocytic U937 cells [sounding rocket]
National Aeronautics and Space Administration —
We investigated differentially regulated genes in human myelomonocytic U937 cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to... -
Federal
International Space Station - Microbial Observatory of Pathogenic Virus Bacteria and Fungi project
National Aeronautics and Space Administration —
This study investigated the interplay between the microbial community of the International Space Station and its crew. Environmental samples were collected from 8... -
Federal
Rodent Research-3-CASIS: Mouse kidney transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
The Heat-Inducible Transcription Factor HsfA2 Enhances Anoxia Tolerance in Arabidopsis
National Aeronautics and Space Administration —
Anoxia induces several heat shock proteins and a heat pre-treatment can acclimatize Arabidopsis seedlings to a subsequent anoxic treatment. In this work we analyzed... -
Federal
Eruca sativa Rocket Science RNA-seq
National Aeronautics and Space Administration —
In the Rocket Science citizen science project Eruca sativa (salad rocket) seeds stored for six months on board of the International Space Station caused delayed crop... -
Federal
An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state
National Aeronautics and Space Administration —
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This... -
Federal
A study of alterations DNA epigenetic modifiincations (5mC and 5hmC) influenced by simulated microgravity in human lymphoblastoid cells
National Aeronautics and Space Administration —
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the... -
Federal
Galactic cosmic radiation induces stable epigenome alterations relevant to human lung cancer
National Aeronautics and Space Administration —
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in... -
Federal
Effects of bedrest and hypoxia on human skeletal muscle miRNA expression
National Aeronautics and Space Administration —
The present study concerns the effects of 21 days of sustained recumbence (bedrest) and hypoxia alone and in combination on skeletal muscle microRNA expression. 14... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This... -
Federal
Transcription profiling of rat to study the effect of hindlimb unloading on healing of medial collateral ligaments 3 weeks after injury
National Aeronautics and Space Administration —
A recent physiological study established that hindlimb unloading of rats at 3 and 7 weeks inhibits healing of injured ligaments resulting in a badly aligned... -
Federal
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Rodent Research-3-CASIS: Mouse liver transcriptomic proteomic and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the...
32 datasets found