21 datasets found
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Federal
Galactic cosmic radiation induces stable epigenome alterations relevant to human lung cancer recent views
National Aeronautics and Space Administration —
Human deep space and planetary travel is limited by uncertainties regarding the health risks associated with exposure to galactic cosmic radiation (GCR) and in... -
Federal
Mouse fecal microbiome after exposure to high LET radiation recent views
National Aeronautics and Space Administration —
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose... -
Federal
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation recent views
National Aeronautics and Space Administration —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Federal
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation recent views
National Aeronautics and Space Administration —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Federal
Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle recent views
National Aeronautics and Space Administration —
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of... -
Federal
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade recent views
National Aeronautics and Space Administration —
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 Gy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 Gy RNA is isolated and labeled using a T7... -
Federal
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland recent views
National Aeronautics and Space Administration —
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation.... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome recent views
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
Gene expression in blood of mice with internal exposure to Cs-137 recent views
National Aeronautics and Space Administration —
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an... -
Federal
IMR90 4hr bystander experiment 0.5Gy alpha particle strip dish format recent views
National Aeronautics and Space Administration —
Radiation affects tissue and cellular integrity at the level of DNA protein and metabolites of the cell and extracellular space. The effects of radiation are not... -
Federal
IMR90 bystander experiment 0.5 Gy alpha particle recent views
National Aeronautics and Space Administration —
The existence of a radiation bystander effect in which non-irradiated cells respond to signals from irradiated cells is well established. It raises concerns for the... -
Federal
Radiation-induced bystander effects and gene expression in cells deficient for RAD9 recent views
National Aeronautics and Space Administration —
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam recent views
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Identifying radiation exposure biomarkers from mouse blood transcriptome recent views
National Aeronautics and Space Administration —
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological... -
Federal
Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays recent views
National Aeronautics and Space Administration —
Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays or 10 cGy or 30 cGy densely ionizing... -
Federal
Transcription profiling of human peripheral blood to development gene expression signatures for practical radiation biodosimetry recent views
National Aeronautics and Space Administration —
To further development of our gene expression approach to biodosimetry we have employed whole genome microarray expression profiling as a discovery platform to... -
Federal
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland recent views
National Aeronautics and Space Administration —
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation.... -
Federal
Growth rate of mammary cancers arising in irradiated mice is associated with pattern of immune infiltrate recent views
National Aeronautics and Space Administration —
To determine how host irradiation affects tumor profiles in 10 month aged mice treated with HZE or gamma irradiation. -
Federal
Gene expression in blood of mice with internal exposure to Cs-137 recent views
National Aeronautics and Space Administration —
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an...
21 datasets found