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Federal
Transcriptional profiling of kidney tissue from mice flown on the Rodent Research Reference Mission-2 (RRRM-2)
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Transcriptional profiling of spleens from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
GLAS/ICESat L2 Sea Ice Altimetry Data (HDF5) V034
National Aeronautics and Space Administration —
GLAH06 is used in conjunction with GLAH05 to create the Level-2 altimetry products. Level-2 altimetry data provide surface elevations for ice sheets (GLAH12), sea ice... -
Federal
Quantifying Cancellous Bone Structural Changes in Microgravity: Axial Skeleton Results from the RR-1 Mission
National Aeronautics and Space Administration —
Objective of this study was to further validate bone degradation in microgravity as site-specific and preferential to weight bearing bone. An objective of this study... -
Federal
Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic, proteomic, and epigenomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
Transcriptional profiling of cerebellums from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-23 missions (RR-23) was to better understand the effects of spaceflight on the eyes, specifically on the structure and function... -
Federal
STS-135: Mouse Liver Transcriptomics using RNA-Seq
National Aeronautics and Space Administration —
Female C57BL/6CR mice were flown onboard STS-135 for 13 days and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in... -
Federal
New insights into the role of lncRNA after spaceflight
National Aeronautics and Space Administration —
We analyzed the transcriptional profile by RNA-sequencing of exosomal content isolated from blood plasma of three astronauts who flew on various ISS missions between... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina boulardi 17 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Relevance of Unfolded Protein Response to Spaceflight-Induced Transcriptional Reprogramming in Arabidopsis
National Aeronautics and Space Administration —
Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human... -
Federal
Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight: Advanced Plant EXperiment (APEX) 03-1 Raw Dataset
National Aeronautics and Space Administration —
This study was conducted to uncover the underlying molecular mechanisms by which microgravity impacts cell wall architecture in the model plant Arabidopsis thaliana... -
Federal
Simulated Galactic Cosmic Ray Exposure Activates Dose-Dependent DNA Repair Response and Downregulates Glucosinolate Pathway in Arabidopsis Seedlings
National Aeronautics and Space Administration —
This study's objective was to develop an understanding of the biological effects of space radiation on plants with the goal of producing fresh food during long... -
Federal
STS-135 Liver Transcriptomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were... -
Federal
Expression data from drosophila melanogaster
National Aeronautics and Space Administration —
Space travel presents unlimited opportunities for exploration and discovery, but requires a more complete understanding of the immunological consequences of long-term... -
Federal
Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight from RR-1 and RR-9 (calcium uptake and Western blot in soleus and tibialis anterior)
National Aeronautics and Space Administration —
It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a... -
Federal
Validation of Methods to Assess the Immunoglobulin Gene Repertoire in Tissues Obtained from Mice on the International Space Station
National Aeronautics and Space Administration —
Spaceflight is known to affect immune cell populations. In particular, splenic B-cell numbers decrease during spaceflight and in ground-based physiological models.... -
Federal
Gene Expression Profile Changes due to Bleomycin-Induced DNA Damage in Human Fibroblasts in Space
National Aeronautics and Space Administration —
To understand gene expression responses in confluent human fibroblast in microgravity conditions to bleomycin treatment. Confluent human fibroblasts AG01522 were... -
Federal
Growth rate of mammary cancers arising in irradiated mice is associated with pattern of immune infiltrate
National Aeronautics and Space Administration —
To determine how host irradiation affects tumor profiles in 10 month aged mice treated with HZE or gamma irradiation. -
Federal
NASA Aircraft Bioaerosol Collector (ABC) -2
National Aeronautics and Space Administration —
Several studies have reported that microorganisms are co-transported with globally dispersed aerosols and that microbial DNA and viable cells have been detected at...