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Rodent Research-3-CASIS: Mouse adrenal gland transcriptomic, proteomic, and epigenomic data

Metadata Updated: August 30, 2025

The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the effectiveness of a potential countermeasure for the loss of muscle and bone mass that occurs during spaceflight. Twenty BALB/c, 12-weeks old female mice (ten controls and ten treated) were flown to the ISS and housed in the Rodent Habitat for 39-42 days. Twenty mice of similar age, sex and strain were used for ground controls housed in identical hardware and matching ISS environmental conditions. Basal controls were housed in standard vivarium cages. Spaceflight, ground controls and basal groups had blood collected, then were euthanized, had one hind limb removed, and finally whole carcasses were stored at -80 C until dissection. All mice in this data set received only the control/sham injection.

Access & Use Information

Public: This dataset is intended for public access and use. License: No license information was provided. If this work was prepared by an officer or employee of the United States government as part of that person's official duties it is considered a U.S. Government Work.

Downloads & Resources

Dates

Metadata Created Date April 11, 2025
Metadata Updated Date August 30, 2025

Metadata Source

Harvested from NASA Data.json

Additional Metadata

Resource Type Dataset
Metadata Created Date April 11, 2025
Metadata Updated Date August 30, 2025
Publisher Open Science Data Repository
Maintainer
Identifier 10.26030/js8g-yq79
Data Last Modified 2025-08-21
Category Biological and Physical Sciences
Public Access Level public
Bureau Code 026:00
Metadata Context https://project-open-data.cio.gov/v1.1/schema/catalog.jsonld
Schema Version https://project-open-data.cio.gov/v1.1/schema
Catalog Describedby https://project-open-data.cio.gov/v1.1/schema/catalog.json
Harvest Object Id 65b88a7f-4bc0-4a9b-a97e-5a8ade755630
Harvest Source Id 58f92550-7a01-4f00-b1b2-8dc953bd598f
Harvest Source Title NASA Data.json
Homepage URL https://lsda.jsc.nasa.gov/scripts/mission/miss.aspx?mis_index=1391;https://lsda.jsc.nasa.gov/Mission/miss/1392
Program Code 026:000
Source Datajson Identifier True
Source Hash 2f5b7271aa1aaded6af51f5ffed993a185d52df18b929a1993abbd944e6cddcd
Source Schema Version 1.1

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