18 datasets found
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Federal
Saunders et al. Amended IVIVE model recent views
U.S. Environmental Protection Agency —
This paper described development of an in vitro/in vivo model that accounts for first pass clearance effects. The model details are contained in the supporting... -
Federal
Open source data summaries - Fish, Rat, and Goat Metabolism Studies recent views
U.S. Environmental Protection Agency —
Public versions of EFSA DAR's - metabolism study summaries for the pesticides; Fluazinam, Halauxifen-methyl, Kresoxim-methyl, Mandestrobin, Tolclofos-methyl in fish... -
Federal
Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals recent views
U.S. Environmental Protection Agency —
This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice... -
Federal
MulticyclicAromaticHydrocarbons rtER Vtg_Kolanczyk_A-bzkz_DataSet 20180828 recent views
U.S. Environmental Protection Agency —
A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC) were... -
Federal
A Comparative Study of Phase I and II Hepatic Microsomal Biotransformation of Phenol in Three Species of Salmonidae: Hydroquinone, Catechol, and Phenylglucuronide Formation recent views
U.S. Environmental Protection Agency —
Dataset for "Kolanczyk, R.C.; Solem, L.E.; Schmieder, P.K.; McKim, J.M., III. A Comparative Study of Phase I and II Hepatic Microsomal Biotransformation of Phenol in... -
Federal
The effects of arsenic speciation on accumulation and toxicity of dietborne arsenic exposures to rainbow trout. recent views
U.S. Environmental Protection Agency —
This dataset provides exposure and effects data for two experiments regarding the dietborne toxicity of inorganic arsenic and selected organoarsenicals on rainbow... -
Federal
Optimized UDP-glucuronosyltransferase (UGT) activity assay for trout liver S9 fractions recent views
U.S. Environmental Protection Agency —
This publication provides an optimized UGT assay for trout liver S9 fractions which can be used to perform in vitro-in vivo extrapolations of measured UGT activity.... -
Federal
THI dataset for ScienceHubJSerrano recent views
U.S. Environmental Protection Agency —
Thiacloprid (THI) is a neonicotinoid insecticide of interest to the USEPA due to its low absorption by crops, greater distribution into the surrounding areas, and... -
Federal
Increased endocrine activity of xenobiotic chemicals as mediated by metabolic activation - data set recent views
U.S. Environmental Protection Agency —
Data set to support the manuscript "Increased endocrine activity of xenobiotic chemicals as mediated by metabolic activation". Contains analytical measurement of... -
Federal
Toxicokinetics of PFOS in rainbow trout recent views
U.S. Environmental Protection Agency —
This ScienceHub entry was developed for the published paper: Consoer et al., 2016, Toxicokinetics of perfluorooctane sulfonate in rainow trout (Oncorhynchus mykiss),... -
Federal
Measurement of kinetic parameters for biotransformation of PAHs by trout liver S9 fractions: Implications for bioaccumulation assessment recent views
U.S. Environmental Protection Agency —
The dataset, which is presented as an Excel spreadsheet, contains all data which is presented as figures in Nichols et al., Measurement of kinetic parameters for... -
Federal
Allometric scaling of hepatic biotransformation in rainbow trout recent views
U.S. Environmental Protection Agency —
This dataset illustrates relationships between body weight and hepatic phase I and phase II metabolic activity in rainbow trout. This dataset is associated with the... -
Federal
Characterization data for trout liver S9 fractions used by Droge et al to measure the in vitro intrinsic clearance of cationic surfactants recent views
U.S. Environmental Protection Agency —
This ScienceHub dataset provides characterization data for a pooled sample of trout liver S9 fractions that was used to study the in vitro intrinsic clearance of... -
Federal
Saunders et al_IVIVE paper_Science Hub_entry_08142020 recent views
U.S. Environmental Protection Agency —
The purpose of is this study was to evaluate the potential for biotransformation in the gastrointestinal tissues (GIT) of fish to impact chemical bioaccumulation. In... -
Federal
Reliability of in vitro methods used to measure intrinsic clearance of hydrophobic organic chemicals by fish: results of an international ring trial_Nichols et al._Science Hub entry_02232018 recent views
U.S. Environmental Protection Agency —
This paper describes the results of an international ring trial (round robin study) of in vitro methods used to measure chemical biotransformation in fish.... -
Federal
Comparison of cryopreserved trout hepatocytes and liver S9 fractions as in vitro tools for bioaccumulation assessment of chemicals that undergo biotransformation in fish recent views
U.S. Environmental Protection Agency —
The purpose of this study was to compare two in vitro systems, cryopreserved trout hepatocytes and trout liver S9 fractions, used to predict in vivo levels of... -
Federal
Estrogenic Activity of Perfluoro Carboxylic and Sulfonic Acids in Rainbow Trout Estrogen Receptor Binding and Liver Slice Vtg mRNA Expression Assays recent views
U.S. Environmental Protection Agency —
Data for "Estrogenic Activity of Perfluoro Carboxylic and Sulfonic Acids in Rainbow Trout Estrogen Receptor Binding and Liver Slice Vtg mRNA Expression Assays. Mark... -
Federal
In Vitro Metabolism of Imidacloprid and Acetamiprid in Rainbow Trout and Rat - Kolanczyk_A-dv4j_SDMP_20190918 recent views
U.S. Environmental Protection Agency —
The current study constitutes the first report of the metabolism of imidacloprid and acetamiprid in rainbow trout. Formation of respective metabolites 5-hydroxy-...
18 datasets found