Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals
This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression assay.
This dataset is associated with the following publication:
Hornung, M., M. Tapper, J. Denny, B. Sheedy, R. Erickson, T. Sulerud, R. Kolanczyk, and P. Schmieder. Avoiding false positives and optimizing identification of true negatives in estrogen receptor binding and agonist/antagonist assays. Applied In vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 3(2): 163-181, (2017).
Resources
1 resource available
-
Trout_ER_Antagonism_Data.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Michael Hornung", "hasEmail": "mailto:hornung.michael@epa.gov" } |
| description | This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression assay. This dataset is associated with the following publication: Hornung, M., M. Tapper, J. Denny, B. Sheedy, R. Erickson, T. Sulerud, R. Kolanczyk, and P. Schmieder. Avoiding false positives and optimizing identification of true negatives in estrogen receptor binding and agonist/antagonist assays. Applied In vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 3(2): 163-181, (2017). |
| distribution |
[ { "title": "Trout_ER_Antagonism_Data.xlsx", "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet", "downloadURL": "https://pasteur.epa.gov/uploads/472/Trout_ER_Antagonism_Data.xlsx" } ] |
| identifier | A-8czj-472 |
| keyword |
[ "antagonist", "competitive binding", "estrogen receptor", "in vitro", "rainbow trout", "vitellogenin" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2017-01-11 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1089/aivt.2016.0021" ] |
| rights |
null
|
| title | Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals |
