Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals
This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression assay.
This dataset is associated with the following publication:
Hornung, M., M. Tapper, J. Denny, B. Sheedy, R. Erickson, T. Sulerud, R. Kolanczyk, and P. Schmieder. Avoiding false positives and optimizing identification of true negatives in estrogen receptor binding and agonist/antagonist assays. Applied In vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 3(2): 163-181, (2017).
Resources
1 resource available
-
Trout_ER_Antagonism_Data.xlsx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Michael Hornung",
"hasEmail": "mailto:hornung.michael@epa.gov"
}
|
| description | This dataset is from screening 94 diverse chemicals for estrogen receptor (ER) activation in a competitive rainbow trout ER binding assay and a trout liver slice vitellogenin mRNA expression assay. This dataset is associated with the following publication: Hornung, M., M. Tapper, J. Denny, B. Sheedy, R. Erickson, T. Sulerud, R. Kolanczyk, and P. Schmieder. Avoiding false positives and optimizing identification of true negatives in estrogen receptor binding and agonist/antagonist assays. Applied In vitro Toxicology. Mary Ann Liebert, Inc., Larchmont, NY, USA, 3(2): 163-181, (2017). |
| distribution |
[
{
"title": "Trout_ER_Antagonism_Data.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/472/Trout_ER_Antagonism_Data.xlsx"
}
]
|
| identifier | A-8czj-472 |
| keyword |
[
"antagonist",
"competitive binding",
"estrogen receptor",
"in vitro",
"rainbow trout",
"vitellogenin"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2017-01-11 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1089/aivt.2016.0021"
]
|
| rights |
null
|
| title | Rainbow trout estrogen receptor (ER) competitive bindng and vitellogenin induction agonism/antagonism data for 94 chemicals |
