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Federal
Comparison of various characteristics of women who do and do not attend for breast cancer screening
U.S. Department of Health & Human Services —
Background Information regarding the characteristics and health of women who do and do not attend for breast cancer screening is limited and representative data are... -
Federal
Asthma and PM
U.S. Department of Health & Human Services —
PM10 (the mass of particles present in the air having a 50% cutoff for particles with an aerodynamic diameter of 10 μm) is the standard measure of particulate air... -
Federal
Interleukin-4 receptor alpha gene variants and allergic disease
U.S. Department of Health & Human Services —
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this... -
Federal
House dust mite barrier bedding for childhood asthma: randomised placebo controlled trial in primary care [ISRCTN63308372]
U.S. Department of Health & Human Services —
Background The house dust mite is the most important environmental allergen implicated in the aetiology of childhood asthma in the UK. Dust mite barrier bedding is... -
Federal
Neurotrophins in bronchial asthma
U.S. Department of Health & Human Services —
Allergic bronchial asthma (BA) is characterized by chronic airway inflammation, development of airway hyperreactivity and recurrent reversible airway obstruction.... -
Federal
The gene encoding interleukin-13: a susceptibility locus for asthma and related traits
U.S. Department of Health & Human Services —
Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2)... -
Federal
Lung surfactant in subacute pulmonary disease
U.S. Department of Health & Human Services —
Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant... -
Federal
Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
U.S. Department of Health & Human Services —
The hygiene hypothesis states that childhood asthma develops as a result of decreased exposure to infectious agents during infancy and early childhood. This results... -
Federal
Th2 cytokines and asthma: an introduction
U.S. Department of Health & Human Services —
Th2 cytokines and asthma: an introduction -
Federal
Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?
U.S. Department of Health & Human Services —
The cellular and molecular mechanisms that are involved in airway hyper-responsiveness are unclear. Current studies suggest that tumor necrosis factor (TNF)-α, a... -
Federal
Human airway xenograft models of epithelial cell regeneration
U.S. Department of Health & Human Services —
Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory... -
Federal
Chemokines and their role in airway hyper-reactivity
U.S. Department of Health & Human Services —
Airway hyper-reactivity is a characteristic feature of many inflammatory lung diseases and is defined as an exaggerated degree of airway narrowing. Chemokines and... -
Federal
Th2 cytokines and asthma — Interleukin-9 as a therapeutic target for asthma
U.S. Department of Health & Human Services —
Asthma is a complex heritable inflammatory disorder of the airways in which the development of clinical disease depends on environmental exposure. It has been well... -
Federal
Mimicking microbial 'education' of the immune system: a strategy to revert the epidemic trend of atopy and allergic asthma?
U.S. Department of Health & Human Services —
Deficient microbial stimulation of the immune system, caused by hygiene, may underly the atopy and allergic asthma epidemic we are currently experiencing. Consistent... -
Federal
New approaches to the modulation of inflammatory processes in airway disease models: ATS 2001, May 18-23, San Francisco
U.S. Department of Health & Human Services —
The 97th American Thoracic Society meeting proved to be an excellent meeting, providing a wealth of new information on inflammatory diseases of the airways. Once... -
Federal
Angiogenesis in the pathogenesis of inflammatory joint and lung diseases
U.S. Department of Health & Human Services —
This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung.... -
Federal
What have transgenic and knockout animals taught us about respiratory disease?
U.S. Department of Health & Human Services —
Over the past decade there has been a significant shift to the use of murine models for investigations into the molecular basis of respiratory diseases, including... -
Federal
Microarray profile of differentially expressed genes in a monkey model of allergic asthma
U.S. Department of Health & Human Services —
Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary... -
Federal
Assessing the knowledge of bronchial asthma among primary health care physicians in Crete: A pre- and post-test following an educational course
U.S. Department of Health & Human Services —
Aim To assess the level of knowledge for bronchial asthma of the primary healthcare physicians serving a rural population on the island of Crete, both before and... -
Federal
Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity
U.S. Department of Health & Human Services —
Background The morbidity and mortality from asthma have markedly increased since the late 1970s. The hospitalization rate, an important marker of asthma severity,...