44 datasets found for "asthma"
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Federal
Asthma and PM
U.S. Department of Health & Human Services —
PM10 (the mass of particles present in the air having a 50% cutoff for particles with an aerodynamic diameter of 10 μm) is the standard measure of particulate air... -
Federal
Interleukin-4 receptor alpha gene variants and allergic disease
U.S. Department of Health & Human Services —
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this... -
Federal
What have transgenic and knockout animals taught us about respiratory disease?
U.S. Department of Health & Human Services —
Over the past decade there has been a significant shift to the use of murine models for investigations into the molecular basis of respiratory diseases, including... -
Federal
Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease
U.S. Department of Health & Human Services —
Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is... -
Federal
Comparison of various characteristics of women who do and do not attend for breast cancer screening
U.S. Department of Health & Human Services —
Background Information regarding the characteristics and health of women who do and do not attend for breast cancer screening is limited and representative data are... -
Federal
Simultaneous identification of
U.S. Department of Health & Human Services —
Background The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the... -
Federal
Chronic obstructive pulmonary disease, asthma and protective effects of food intake: from hypothesis to evidence?
U.S. Department of Health & Human Services —
Evidence for a role of diet in asthma and chronic obstructive pulmonary disease (COPD) has been accumulating rapidly over the past decade. Associations have been... -
Federal
Airway obstruction in asthma: does the response to a deep inspiration matter?
U.S. Department of Health & Human Services —
Airway hyperresponsiveness in asthma may not be a problem of too much airway smooth muscle strength. Rather, it may be a problem of too little of the factors that... -
Federal
Neurotrophins in bronchial asthma
U.S. Department of Health & Human Services —
Allergic bronchial asthma (BA) is characterized by chronic airway inflammation, development of airway hyperreactivity and recurrent reversible airway obstruction.... -
Federal
Th2 cytokines and asthma — Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists
U.S. Department of Health & Human Services —
Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion... -
Federal
Lung surfactant in subacute pulmonary disease
U.S. Department of Health & Human Services —
Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant... -
Federal
House dust mite barrier bedding for childhood asthma: randomised placebo controlled trial in primary care [ISRCTN63308372]
U.S. Department of Health & Human Services —
Background The house dust mite is the most important environmental allergen implicated in the aetiology of childhood asthma in the UK. Dust mite barrier bedding is... -
Federal
Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
U.S. Department of Health & Human Services —
The hygiene hypothesis states that childhood asthma develops as a result of decreased exposure to infectious agents during infancy and early childhood. This results... -
Federal
Chemokines and their role in airway hyper-reactivity
U.S. Department of Health & Human Services —
Airway hyper-reactivity is a characteristic feature of many inflammatory lung diseases and is defined as an exaggerated degree of airway narrowing. Chemokines and... -
Federal
Human airway xenograft models of epithelial cell regeneration
U.S. Department of Health & Human Services —
Regeneration and restoration of the airway epithelium after mechanical, viral or bacterial injury have a determinant role in the evolution of numerous respiratory... -
Federal
Th2 cytokines and asthma — Interleukin-9 as a therapeutic target for asthma
U.S. Department of Health & Human Services —
Asthma is a complex heritable inflammatory disorder of the airways in which the development of clinical disease depends on environmental exposure. It has been well... -
Federal
Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells
U.S. Department of Health & Human Services —
Phosphoinositide 3-kinases (PI-3Ks) are enzymes that generate lipid second messenger molecules, resulting in the activation of multiple intracellular signalling... -
Federal
Th2 cytokines and asthma: an introduction
U.S. Department of Health & Human Services —
Th2 cytokines and asthma: an introduction -
Federal
Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma
U.S. Department of Health & Human Services —
Asthma is the most common chronic childhood disease in the developed nations, and is a complex disease that has high social and economic costs. Studies of the genetic... -
Federal
Patent AT-E399763-T1: [Translated] PROTEASE INHIBITORS
U.S. Department of Health & Human Services —
A monoacyl semicarbazide of the general formula (I) nor a pharmaceutically acceptable salt or ester thereof, is capable of selectively inhibiting dipeptidyl-peptidase...
44 datasets found for "asthma"