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Federal
Intensive care management of organophosphate insecticide poisoning
U.S. Department of Health & Human Services —
Introduction Organophosphate (OP) insecticides inhibit both cholinesterase and pseudo-cholinesterase activities. The inhibition of acetylcholinesterase causes... -
Federal
Icodextrin as salvage therapy in peritoneal dialysis patients with refractory fluid overload
U.S. Department of Health & Human Services —
Background Icodextrin is a high molecular weight, starch-derived glucose polymer, which is capable of inducing sustained ultrafiltration over prolonged (12–16 hour)... -
Federal
Factors explaining variance in perceived pain in women with fibromyalgia
U.S. Department of Health & Human Services —
Background We hypothesized that a substantial proportion of the subjectively experienced variance in pain in fibromyalgia patients would be explained by psychological... -
Federal
Omapatrilat normalizes renal function curve in spontaneously hypertensive rats
U.S. Department of Health & Human Services —
Background The present study was designed to analyze the chronic renal response to omapatrilat, a new vasopeptidase inhibitor, in spontaneously hypertensive rats... -
Federal
Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (
U.S. Department of Health & Human Services —
Background: Differences in responses to bacterial surface lipopolysaccharides (LPSs) are apparent between and within mammalian species. It has been shown in mice that... -
Federal
Craniodental variation among Macaques (
U.S. Department of Health & Human Services —
Background In terms of structure and function, the skull is one of the most complicated organs in the body. It is also one of the most important parts in terms of... -
Federal
New insights into the effects on blood pressure of diets low in salt and high in fruits and vegetables and low-fat dairy products
U.S. Department of Health & Human Services —
Results from the recent Dietary Approaches to Stop Hypertension (DASH)-Sodium trial provide the latest evidence concerning the effects of dietary patterns and sodium... -
Federal
A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes
U.S. Department of Health & Human Services —
Background: Correlations between genome composition (in terms of GC content) and usage of particular codons and amino acids have been widely reported, but poorly... -
Federal
Elevated nerve growth factor and neurotrophin-3 levels in cerebrospinal fluid of children with hydrocephalus
U.S. Department of Health & Human Services —
Background Elevated intracranial pressure (ICP) resulting from impaired drainage of cerebrospinal fluid (CSF) causes hydrocephalus with damage to the central nervous... -
Federal
Identifying older diabetic patients at risk of poor glycemic control
U.S. Department of Health & Human Services —
Background Optimal glycemic control prevents the onset of diabetes complications. Identifying diabetic patients at risk of poor glycemic control could help promoting... -
Federal
The effect of continuous positive airway pressure (CPAP) on renal vascular resistance: the influence of renal denervation
U.S. Department of Health & Human Services —
Objective: To non-invasively study the effects of continuous positive airway pressure breathing (CPAP) on renal vascular resistance in normal subjects and renal... -
Federal
A Prospective Study of Pravastatin in the Elderly at Risk (PROSPER): Screening Experience and Baseline Characteristics
U.S. Department of Health & Human Services —
Background PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the... -
Federal
Upregulation of nitric oxide synthase in mice with severe hypoxia-induced pulmonary hypertension
U.S. Department of Health & Human Services —
Background The importance of nitric oxide (NO) in hypoxic pulmonary hypertension has been demonstrated using nitric oxide synthase (NOS) knockout mice. In that model... -
Federal
Effect of mivacurium 200 and 250 μg/kg in infants during isoflurane anesthesia: a randomized controlled trial [ISRCTN07742712]
U.S. Department of Health & Human Services —
Background Infants usually respond differently to a neuromuscular relaxant compared to children or adults. Isoflurane is commonly used as an anesthetic gas in... -
Federal
Inhaled nitric oxide reverses cell-free hemoglobin-induced pulmonary hypertension and decreased lung compliance. Preliminary results
U.S. Department of Health & Human Services —
Background: In order to test the hypothesis that inhaled nitric oxide (NO) reverses the pulmonary hypertension induced by αα-diaspirin crosslinked hemoglobin (ααHb),... -
Federal
Atrial natriuretic peptide infusion and nitric oxide inhalation in patients with acute respiratory distress syndrome
U.S. Department of Health & Human Services —
Aim: To study the effects of infusion of atrial natriuretic peptide (ANP) versus the inhalation of nitric oxide (NO) in patients with an early acute respiratory... -
Federal
The method of bladder drainage in spinal cord injury patients may influence the histological changes in the mucosa of neuropathic bladder – a hypothesis
U.S. Department of Health & Human Services —
Background In spinal cord injury (SCI) patients, no correlation was found between the number of bladder infections per year, the period since injury, the neurologic... -
Federal
Catecholamine-induced interleukin-10 release: a key mechanism in systemic immunodepression after brain injury
U.S. Department of Health & Human Services —
Background: Infections after severe brain injury or polytrauma are still a problem, and may be the result of a brain-mediated disturbed systemic immunoreactivity. The... -
Federal
Long-term vitamin E supplementation fails to reduce lipid peroxidation in people at cardiovascular risk: analysis of underlying factors
U.S. Department of Health & Human Services —
Background Antioxidant supplementation with vitamin E had no effect in the prevention of cardiovascular diseases (CVD) in three recent large, randomized clinical... -
Federal
Mouse skin passage of a
U.S. Department of Health & Human Services —
Background Streptolysin S (SLS), the oxygen-stable hemolysin of Streptococcus pyogenes, has recently been shown to be encoded by the sagA/pel gene. Mutants lacking...