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Federal
An MCASE approach to the search of a cure for Parkinson's Disease.
U.S. Department of Health & Human Services —
Background Parkinson's disease is caused by a dopamine deficiency state in the fore brain area. Dopamine receptor agonists, MAO-B inhibitors, and N-Methyl-D-Aspartate... -
Federal
Use of complementary/alternative therapies by women with advanced-stage breast cancer
U.S. Department of Health & Human Services —
Background This study sought to describe the pattern of complementary/alternative medicine (CAM) use among a group of patients with advanced breast cancer, to examine... -
Federal
The diagnostic value of liver biopsy
U.S. Department of Health & Human Services —
Background Since the introduction of molecular diagnostic tools such as markers for hepatitis C and different autoimmune diseases, liver biopsy is thought to be... -
Federal
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol
U.S. Department of Health & Human Services —
Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket.... -
Federal
Impact of false-positive mammography on subsequent screening attendance and risk of cancer
U.S. Department of Health & Human Services —
Background One area of concern within the largely successful UK National Health Service breast screening programme is the relatively high proportion of women showing... -
Federal
Long term benzodiazepine use for insomnia in patients over the age of 60: discordance of patient and physician perceptions
U.S. Department of Health & Human Services —
Background The aim of this study was to determine and compare patients' and physicians' perceptions of benefits and risks of long term benzodiazepine use for insomnia... -
Federal
Food intakes and preferences of hospitalised geriatric patients
U.S. Department of Health & Human Services —
Background A cross sectional survey was carried out on 120 hospitalised geriatric patients aged 60 and above in Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur... -
Federal
Staphylococcal peptidoglycans induce arthritis
U.S. Department of Health & Human Services —
Staphylococcus aureus is one of the most important pathogens in septic arthritis. To analyse the arthritogenic properties of staphylococcal peptidoglycan (PGN),... -
Federal
Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices
U.S. Department of Health & Human Services —
Background Recently a hyperthermic rat hippocampal slice model system has been used to investigate febrile seizure pathophysiology. Our previous data indicates that... -
Federal
Phospholipase Cδ regulates germination of
U.S. Department of Health & Human Services —
Background Many eukaryotes, including plants and fungi make spores that resist severe environmental stress. The micro-organism Dictyostelium contains a single... -
Federal
Prevalence and risk factors for vaginal
U.S. Department of Health & Human Services —
Background Diabetes mellitus increases the rate of vaginal colonization and infection with Candida species Methods We surveyed women with diabetes receiving care at... -
Federal
Binding of the baculovirus very late expression factor 1 (VLF-1) to different DNA structures
U.S. Department of Health & Human Services —
Background Baculovirus genomes encode a gene called very late expression factor 1 (VLF-1) that is a member of the integrase (Int) family of proteins. In this report... -
Federal
Pancreatic hyperamylasemia during acute gastroenteritis: incidence and clinical relevance
U.S. Department of Health & Human Services —
Background Many case reports of acute pancreatitis have been reported but, up to now, pancreatic abnormalities during acute gastroenteritis have not been studied... -
Federal
The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
U.S. Department of Health & Human Services —
Background The proper balance between epithelial cell proliferation, quiescence, and apoptosis during development is mediated by the specific temporal and spatial... -
Federal
Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes
U.S. Department of Health & Human Services —
Background It has become increasingly clear that β-cell failure plays a critical role in the pathogenesis of type 2 diabetes. Free-radical mediated β-cell damage has... -
Federal
Effect of mivacurium 200 and 250 μg/kg in infants during isoflurane anesthesia: a randomized controlled trial [ISRCTN07742712]
U.S. Department of Health & Human Services —
Background Infants usually respond differently to a neuromuscular relaxant compared to children or adults. Isoflurane is commonly used as an anesthetic gas in... -
Federal
Self-medication and non-doctor prescription practices in Pokhara valley, Western Nepal: a questionnaire-based study
U.S. Department of Health & Human Services —
Background Self-medication and non-doctor prescribing of drugs is common in developing countries. Complementary and alternative medications, especially herbs, are... -
Federal
Clinical review: Splanchnic ischaemia
U.S. Department of Health & Human Services —
Inadequate splanchnic perfusion is associated with increased morbidity and mortality, particularly if liver dysfunction coexists. Heart failure, increased intra-... -
Federal
Cloning and expression of the rabbit prostaglandin EP2 receptor
U.S. Department of Health & Human Services —
Background Prostaglandin E2 (PGE2) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence... -
Federal
The (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals
U.S. Department of Health & Human Services —
Background The human NOTCH4 gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiological roles. In a British linkage study, NOTCH4...