145 datasets found for "chronic disease indicators"
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Federal
A new direction in the pathogenesis of idiopathic pulmonary fibrosis?
U.S. Department of Health & Human Services —
A recent review article suggested that idiopathic pulmonary fibrosis (IPF) is a disease that is associated more with abnormal wound healing than with inflammation.... -
Federal
Clues to the etiology of autoimmune diseases through analysis of immunoglobulin genes
U.S. Department of Health & Human Services —
The role of autoantibodies in the etiology of autoimmune diseases remains unclear. However, an examination of the sequences of these autoantibodies can be... -
Federal
Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis
U.S. Department of Health & Human Services —
The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining... -
Federal
Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies
U.S. Department of Health & Human Services —
Human tumour necrosis factor (TNF)-like weak inducer of apoptosis (hTWEAK) and two anti-hTWEAK mAbs were tested for their ability to elicit or block inflammatory... -
Federal
Anti-cytokine therapy in chronic destructive arthritis
U.S. Department of Health & Human Services —
Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are considered to be master cytokines in chronic, destructive arthritis. Therapeutic approaches in rheumatoid... -
Federal
Helium oxygen mixtures in the intensive care unit
U.S. Department of Health & Human Services —
Heliox, a mixture of helium and oxygen, has a density that is less than that of air. Breathing heliox leads to a reduction in resistance to flow within the airways,... -
Federal
Smoking, season, and detection of
U.S. Department of Health & Human Services —
Background The prevalence and role of Chlamydia pneumoniae in chronic obstructive pulmonary disease (COPD) remain unclear. Methods Peripheral blood mononuclear cells... -
Federal
The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease
U.S. Department of Health & Human Services —
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought... -
Federal
Association of circulating
U.S. Department of Health & Human Services —
Background Chlamydia pneumoniae antigens, nucleic acids, or intact organisms have been detected in human atheroma. However, the presence of antibody does not predict... -
Federal
NF-kappaB in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction
U.S. Department of Health & Human Services —
The transcription factor NF-κB has been well recognized as a pivotal regulator of inflammation in rheumatoid arthritis (RA), but recent developments revealed a broad... -
Federal
Down-regulation of the alpha-2C adrenergic receptor: involvement of a serine/threonine motif in the third cytoplasmic loop
U.S. Department of Health & Human Services —
Background The mechanisms by which alpha-2 adrenergic receptors are down-regulated following chronic exposure to agonist are not well understood. Interestingly, the... -
Federal
Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis
U.S. Department of Health & Human Services —
Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than... -
Federal
The genetics of chronic obstructive pulmonary disease
U.S. Department of Health & Human Services —
Chronic obstructive pulmonary disease (COPD) is a significant cause of global morbidity and mortality. Previous studies have shown that COPD aggregates in families,... -
Federal
Need for critical care in gynaecology: a population-based analysis
U.S. Department of Health & Human Services —
Introduction The purpose of this study was to note potential gynaecological risk factors leading to intensive care and to estimate the frequency, costs and outcome of... -
Federal
An examination of the Apo-1/Fas promoter Mva I polymorphism in Japanese patients with multiple sclerosis
U.S. Department of Health & Human Services —
Background The Apo-1/Fas (CD95) molecule is an apoptosis-signaling cell surface receptor belonging to the tumor necrosis factor (TNF) receptor family. Both Fas and... -
Federal
Bilateral linear scleroderma "en coup de sabre" associated with facial atrophy and neurological complications
U.S. Department of Health & Human Services —
Background Linear scleroderma "en coup de sabre" (LSCS) usually affects one side of the face and head in the frontoparietal area with band-like indurated skin... -
Federal
Chronic obstructive pulmonary disease, asthma and protective effects of food intake: from hypothesis to evidence?
U.S. Department of Health & Human Services —
Evidence for a role of diet in asthma and chronic obstructive pulmonary disease (COPD) has been accumulating rapidly over the past decade. Associations have been... -
Federal
A comparative study of gallstones from children and adults using FTIR spectroscopy and fluorescence microscopy
U.S. Department of Health & Human Services —
Background Cholelithiasis is the gallstone disease (GSD) where stones are formed in the gallbladder. The main function of the gallbladder is to concentrate bile by... -
Federal
Tumour Fas ligand:Fas ratio greater than 1 is an independent marker of relative resistance to tamoxifen therapy in hormone receptor positive breast cancer
U.S. Department of Health & Human Services —
Background The objective of the present study was to examine the prognostic and predictive significance of the apoptosis-related marker Fas ligand (FasL):Fas ratio in... -
Federal
Immune ablation and stem-cell therapy in autoimmune disease: Clinical experience
U.S. Department of Health & Human Services —
In the past 5 years, around 350 patients have received haematopoietic stem cell (HSC) transplantation for an autoimmune disease, with 275 of these registered in an...
145 datasets found for "chronic disease indicators"