Search datasets
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A study was done to determine if the differentiation and activation phenotype of T cells in synovial fluid (SF) from patients with juvenile idiopathic arthritis (JIA) is associated with T-cell...
Search relevance: 289.87 | Views last month: 0 | Catalog Last Checked: July 31, 2026 at 09:18 PM -
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (mg). Immunosuppression during spaceflight is a major barrier to safe...
Search relevance: 264.47 | Views last month: 0 | Catalog Last Checked: September 06, 2025 at 01:21 PM -
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during spaceflight is a major barrier to safe...
Search relevance: 258.31 | Views last month: 0 | Catalog Last Checked: April 13, 2026 at 04:04 PM -
Background Various microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC), determining their ability to interact with naïve T cells and to produce...
Search relevance: 230.39 | Views last month: 12 | Catalog Last Checked: July 31, 2026 at 09:45 PM -
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during spaceflight is a major barrier to safe...
Search relevance: 205.07 | Views last month: 2 | Catalog Last Checked: June 23, 2026 at 09:48 PM -
Background Activation of human resting T lymphocytes results in an immediate increase in protein synthesis. The increase in protein synthesis after 16–24 h has been linked to the...
Search relevance: 87.04 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 10:00 PM -
Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Search relevance: 86.54 | Views last month: 0 | Catalog Last Checked: July 31, 2026 at 08:58 PM -
Background Gene transfer studies in primary T cells have suffered from the limitations of conventional viral transduction or transfection techniques. Replication-defective adenoviral...
Search relevance: 82.69 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 09:06 PM -
The synovial tissue in rheumatoid arthritis (RA) patients is enriched with mature antigen presenting cells (APCs) and many T lymphocytes. Interactions between APCs and T cells are essential for...
Search relevance: 80.28 | Views last month: 7 | Catalog Last Checked: July 31, 2026 at 09:07 PM -
Mechanisms whereby T lymphocytes contribute to synovial inflammation in rheumatoid arthritis are poorly understood. Here we review data that indicate an important role for cell contact between...
Search relevance: 78.74 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 09:15 PM -
In rheumatoid arthritis, T cells and B cells participate in the immune responses evolving in the synovial lesions. Interaction between T cells and B cells is probably antigen specific because...
Search relevance: 75.69 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 10:01 PM -
CD8+ T cells dominate the lymphocyte population in synovial fluid in chronic inflammatory arthritis. It is known that these CD8+ T cells are often clonally or oligoclonally expanded, but...
Search relevance: 75.05 | Views last month: 2 | Catalog Last Checked: July 31, 2026 at 10:04 PM -
After activation CD4+ helper T cells differentiate into T-helper (Th) 1 or Th2 effector cells. These two subsets are characterized by their distinct cytokine expression pattern and the immune...
Search relevance: 73.50 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 09:40 PM -
B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the newly discovered role of...
Search relevance: 71.70 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 09:02 PM -
Background Intrathymic development and selection of the T lymphocyte repertoire is restricted by the interactions of the T cell antigen receptor and CD4 or CD8 co-receptors with self...
Search relevance: 67.35 | Views last month: 0 | Catalog Last Checked: July 31, 2026 at 09:13 PM -
Background T cells from HIV+ and aged individuals show parallels in terms of suppressed proliferative activity and interleukin-2 (I1-2) production and an increased number of CD8+ CD28- T...
Search relevance: 65.44 | Views last month: 1 | Catalog Last Checked: July 31, 2026 at 08:58 PM -
Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) are common, frequently related conditions in people generally over 50 years of age. Most studies have shown an...
Search relevance: 61.67 | Views last month: 2 | Catalog Last Checked: July 31, 2026 at 09:29 PM -
The intricate interactions that regulate relationships between endogenous tissue cells and infiltrating immune cells in the rheumatic joint, particularly in rheumatoid arthritis (RA), were the...
Search relevance: 60.75 | Views last month: 0 | Catalog Last Checked: July 31, 2026 at 09:50 PM -
Background NFATp is one member of a family of transcriptional activators whose nuclear accumulation and hence transcriptional activity is regulated in mammalian cells. Human NFATp exists...
Search relevance: 60.63 | Views last month: 0 | Catalog Last Checked: July 31, 2026 at 10:01 PM -
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression is poorly understood, but...
Search relevance: 59.96 | Views last month: 6 | Catalog Last Checked: July 31, 2026 at 09:53 PM
