Found 51 datasets matching filters. (clear all filters)
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Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7 amplification Arcturus kit for...
Search relevance: 1.00 | Views last month: 10 | Catalog Last Checked: May 06, 2026 at 07:44 PM -
The purpose of this study was to evaluate transcriptional changes in mouse skin using a ground-based model for spaceflight. This model includes prolonged unloading and low-dose irradiation....
Search relevance: 1.00 | Views last month: 6 | Catalog Last Checked: May 06, 2026 at 07:44 PM -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 1.00 | Views last month: 4 | Catalog Last Checked: May 06, 2026 at 07:44 PM -
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of 2100 nuclear genes encoding...
Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: May 06, 2026 at 07:44 PM -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 08, 2025 at 03:01 AM -
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation. RNA was isolated and microarray...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 06, 2025 at 01:21 PM -
Here we present a whole-genome survey of the murine transcriptomic response to physiologically-relevant radiation doses 2 and 8 Gy. There are 18 distinct biological samples here. Mice were exposed...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: September 06, 2025 at 01:20 PM -
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:50 AM -
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:28 AM -
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the contribution of genome level...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:48 AM -
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an extended period of time potentially...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: April 20, 2026 at 04:12 PM -
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of radiation exposure to humans. The...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: April 13, 2026 at 04:04 PM -
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to predict exposure dose for use...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:31 AM -
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: January 31, 2026 at 08:19 PM -
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling. Thus identification and...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:26 AM -
Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated controls or those irradiated with...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: October 06, 2025 at 04:18 AM -
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not been fully addressed for gene...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: January 31, 2026 at 08:19 PM -
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not been fully addressed for gene...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: February 14, 2026 at 08:23 PM -
The existence of a radiation bystander effect in which non-irradiated cells respond to signals from irradiated cells is well established. It raises concerns for the interpretation of risks from...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:47 AM -
Certain mouse strains such as CBA C3H and RFM have high incidence of radiation-induced acute myeloid leukemia (AML). The data in this series wer generated by using spleen DNA from CBA mice which...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: August 04, 2025 at 08:46 AM
