Found 97 datasets matching filters.
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Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene expression profiles obtained...
Search relevance: 1.00 | Views last month: 6 | Catalog Last Checked: September 07, 2025 at 11:54 AM -
Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The conventional use of a single gene for...
Search relevance: 1.00 | Views last month: 5 | Catalog Last Checked: September 07, 2025 at 01:35 PM -
Background Proximal chromosome 15q is implicated in neurodevelopmental disorders including Prader-Willi and Angelman syndromes, autistic disorder and developmental abnormalities...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: September 07, 2025 at 11:17 AM -
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: September 07, 2025 at 11:53 PM -
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends not on genomic...
Search relevance: 1.00 | Views last month: 3 | Catalog Last Checked: September 07, 2025 at 03:24 PM -
Background Genome wide transcriptome maps can provide tools to identify candidate genes that are over-expressed or silenced in certain disease tissue and increase our understanding of...
Search relevance: 1.00 | Views last month: 2 | Catalog Last Checked: September 07, 2025 at 12:40 PM -
Background Gene expression profiling among different tissues is of paramount interest in various areas of biomedical research. We have developed a novel method (DADA, Digital Analysis of...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 01:36 PM -
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to limited accessibility...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 11:01 AM -
Genomics, or the study of genes and their function, is a burgeoning field with many new technologies. In the present review, we explore the application of genomic approaches to the study of...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 12:02 PM -
Background Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic hormone (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The regulatory mechanisms...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 12:18 PM -
Background High-density oligonucleotide arrays (HDONAs) are a powerful tool for assessing differential mRNA expression levels. To establish the statistical significance of an observed...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 01:53 PM -
Background Versatile transgenic manipulation of skeletal muscle requires knowledge of the expression profiles of diverse promoter/enhancer elements in the transcriptionally specialized...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 07:14 AM -
Background We have used commercially available cDNA arrays to identify EphB4 as a gene that is up-regulated in colon cancer tissue when compared with matched normal tissue from the same...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 09:13 AM -
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however, hampered efforts to...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 12:09 PM -
Background Drugs & used in anticancer chemotherapy have severe effects upon the cellular transcription and replication machinery. From in vitro studies it has become clear that these...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 11:28 PM -
Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional study of newly...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 07:38 PM -
Background The gene expression pattern in tumor cells differs from that in corresponding normal cells. In order to identify differentially expressed genes in colorectal tumors and normal...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 07:28 AM -
Background Current methodology often cannot distinguish second primary breast cancers from multifocal disease, a potentially important distinction for clinical management. In the present...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 07:29 PM -
Background The sequences encoding the yeast RNA polymerase II (RPB) subunits are single copy genes. Results While those characterized so far for the...
Search relevance: 1.00 | Views last month: 1 | Catalog Last Checked: September 07, 2025 at 01:34 PM -
Background: Over the past five years, interest in and use of DNA array technology has increased dramatically, and there has been a surge in demand for different types of arrays. Although...
Search relevance: 1.00 | Views last month: 0 | Catalog Last Checked: September 07, 2025 at 06:46 PM
