116 datasets found
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Federal
Analysis of a human brain transcriptome map
U.S. Department of Health & Human Services —
Background Genome wide transcriptome maps can provide tools to identify candidate genes that are over-expressed or silenced in certain disease tissue and increase our... -
Federal
Plant Expression Database
Department of Agriculture —
[NOTE: PLEXdb is no longer available online. Oct 2019.] PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens.... -
Federal
Data from: Genomic structural differences between cattle and River Buffalo identified through comparative genomic and transcriptomic analysis
Department of Agriculture —
Water buffalo (Bubalus bubalis L.) is an important livestock species worldwide. Like many other livestock species, water buffalo lacks high quality and continuous... -
Federal
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol
U.S. Department of Health & Human Services —
Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket.... -
Federal
Little qualitative RNA misexpression in sterile male F
U.S. Department of Health & Human Services —
Background Although the genetics of hybrid sterility has been the subject of evolutionary studies for over sixty years, no one has shown the reason(s) why alleles... -
Federal
Analysis of strain and regional variation in gene expression in mouse brain
U.S. Department of Health & Human Services —
Background We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains.... -
Federal
Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts
U.S. Department of Health & Human Services —
Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional... -
Federal
Vector algebra in the analysis of genome-wide expression data
U.S. Department of Health & Human Services —
Background Data from thousands of transcription-profiling experiments in organisms ranging from yeast to humans are now publicly available. How best to analyze these... -
Federal
Survey of transcripts in the adult
U.S. Department of Health & Human Services —
Background: Classic methods of identifying genes involved in neural function include the laborious process of behavioral screening of mutagenized flies and then... -
Federal
Receptor protein tyrosine kinase EphB4 is up-regulated in colon cancer
U.S. Department of Health & Human Services —
Background We have used commercially available cDNA arrays to identify EphB4 as a gene that is up-regulated in colon cancer tissue when compared with matched normal... -
Federal
Evaluation of differential gene expression during behavioral development in the honeybee using microarrays and northern blots
U.S. Department of Health & Human Services —
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however,... -
Federal
Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer
U.S. Department of Health & Human Services —
Background Genome-wide or application-targeted microarrays containing a subset of genes of interest have become widely used as a research tool with the prospect of... -
Federal
Normalization and analysis of DNA microarray data by self-consistency and local regression
U.S. Department of Health & Human Services —
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression... -
Federal
HepRG exposed to microcystin LR and RR gene expression
U.S. Environmental Protection Agency —
RNA-seq data from HepaRG cells exposed for 2 hours to microcystin-LR and -RR at multiple concentrations each. This dataset is associated with the following... -
Federal
Within the fold: assessing differential expression measures and reproducibility in microarray assays
U.S. Department of Health & Human Services —
Fold-change' cutoffs have been widely used in microarray assays to identify genes that are differentially expressed. More accurate measures are required to identify... -
Federal
"In-gel" purified ditags direct synthesis of highly efficient SAGE Libraries
U.S. Department of Health & Human Services —
Background SAGE (serial analysis of gene expression) is a recently developed technique for systematic analysis of eukaryotic transcriptomes. The most critical step in... -
Federal
Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients
U.S. Department of Health & Human Services —
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to... -
Federal
Transcriptional territories in the genome
U.S. Department of Health & Human Services —
An analysis of numerous Drosophila microarray experiments reveals that the genome has many large groups of adjacent genes that are expressed similarly but are not... -
Federal
Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
U.S. Department of Health & Human Services —
Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene... -
Federal
A necdin/MAGE-like gene in the chromosome 15 autism susceptibility region: expression, imprinting, and mapping of the human and mouse orthologues
U.S. Department of Health & Human Services —
Background Proximal chromosome 15q is implicated in neurodevelopmental disorders including Prader-Willi and Angelman syndromes, autistic disorder and developmental...
116 datasets found