The tabular data tables in this product include detection frequency and benchmark exceedances of agricultural pesticides in surface water samples collected in rivers and streams. The data are a product of a national-scale assessment of the toxicity of 221 pesticides at 74 sites during water years 2013 - 2017 conducted by the U.S. Geological Survey National Water Quality Pesticide Monitoring Program. Data were collected to 1) determine where and how often pesticides are detected in surface waters, and 2) identify regions in the continental United States that had streams with a higher risk of potential pesticide toxicity by comparing concentrations to both aquatic-life and human-health benchmarks.