This data release contains two tabular data sets of water-quality data collected on the East Fork Carson River. EFCR_CQW.xlsx is a Microsoft Excel workbook containing continuous water-quality data collected by the Nevada Division of Environmental Protection (NDEP) at a site on the East Fork Carson River over two time periods in 2010 and 2012. Data were collected at U.S. Geological Survey site number 385755119473704, East Fork Carson River near Muller Lane downstream transect, also referred to as "SDT" in the larger work. Stream temperature, pH, dissolved oxygen, and specific conductance were measured at 5 to 10 minute intervals from August 3-September 29, 2010 and from July 20-August 17, 2012. EFCR_StreamProfiles.xlsx is Microsoft Excel workbook containing water-quality data collected by Nevada Division of Environmental Protection on August 2 and September 25, 2012, along a reach of the East Fork Carson River. Specific conductance was measured about every 2 minutes along an approximately 1.5-mile reach of the East Fork Carson River on August 2 and along an approximately 2.5-mile reach of the East Fork Carson River on September 25. The data sets are also presented in comma-separated values (CSV) files.