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Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity
The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis.
This dataset is associated with the following publication:
Saili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, and T. Knudsen. Systems Modeling of Developmental Vascular Toxicity. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, NETHERLANDS, 15(1): 55-63, (2019).
Resources
1 resource available
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https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "Thomas Knudsen", "hasEmail": "mailto:knudsen.thomas@epa.gov" } |
| description | The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis. This dataset is associated with the following publication: Saili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, and T. Knudsen. Systems Modeling of Developmental Vascular Toxicity. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, NETHERLANDS, 15(1): 55-63, (2019). |
| distribution |
[ { "title": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos", "accessURL": "https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos" } ] |
| identifier | https://doi.org/10.23719/1503433 |
| keyword |
[ "5HPP-33", "TNP-470", "Tox21", "ToxCast", "adverse outcome pathway", "angiogenesis", "tipping points", "vEmbryo", "virtual embryo", "virtual tissues" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-02-27 |
| programCode |
[ "020:095" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1016/j.cotox.2019.04.004" ] |
| rights |
null
|
| title | Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity |
