Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands
G-protein-coupled receptors (GPCRs) are the largest and most diverse family of transmembrane receptors. A pylogenetic analysis shows the overall relationship of 277 human GPCRs. An emphasis on receptors with no identified natural ligand may prove valuable for identification of the ligands of 'orphan' receptors.
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "009:25" ] |
| contactPoint |
{ "fn": "NIH", "@type": "vcard:Contact", "hasEmail": "mailto:info@nih.gov" } |
| description | G-protein-coupled receptors (GPCRs) are the largest and most diverse family of transmembrane receptors. A pylogenetic analysis shows the overall relationship of 277 human GPCRs. An emphasis on receptors with no identified natural ligand may prove valuable for identification of the ligands of 'orphan' receptors. |
| distribution |
[ { "@type": "dcat:Distribution", "title": "Official Government Data Source", "mediaType": "text/html", "description": "Visit the original government dataset for complete information, documentation, and data access.", "downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133447/" } ] |
| identifier | https://healthdata.gov/api/views/xcyy-6mx7 |
| issued | 2025-07-14 |
| keyword |
[ "g-protein-coupled-receptors", "ligand-prediction", "nih", "orphan-receptors", "phylogenetic-analysis" ] |
| landingPage | https://healthdata.gov/d/xcyy-6mx7 |
| modified | 2025-09-06 |
| programCode |
[ "009:033" ] |
| publisher |
{ "name": "National Institutes of Health", "@type": "org:Organization" } |
| theme |
[ "NIH" ] |
| title | Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands |
