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Background Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often share similar...
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G-protein-coupled receptors (GPCRs) are the largest and most diverse family of transmembrane receptors. A pylogenetic analysis shows the overall relationship of 277 human GPCRs. An emphasis on...
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Previous studies have shown that several agents that stimulate heptahelical G-protein coupled receptors activate the extracellular signal regulated kinases ERK1 (p44mapk) and ERK2 (p42mapk) in...
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