Climate change is a pervasive and growing global threat to the supply and demand of ecosystem goods and services that maintain human well-being. A recent review found that the impacts of climate change on ecosystem services are sometimes mixed, posing challenges for managers who need to adapt to these changes. We expand on earlier work by exploring drivers of varying responses of ecosystem services to climate within studies. We conducted a systematic review of English-language papers directly assessing climate change impacts on the supply, demand, or monetary value of ‘provisioning services’, ‘regulating services’, or ‘cultural services’. Ultimately, we extracted data from 44 papers published from December 2014 to March 2018. In addition to recording direct climate impacts, we extracted data regarding climate interactions with non-climate drivers (e.g., land use change), study context (e.g., spatial scale, location, ecosystem) and methodology, characteristics and interactions between services, whether and how uncertainty was assessed, and implications for decision-making. To answer our core research question, we extracted data reflecting drivers of mixed responses (e.g., variation in ecosystem service responses over space, ecosystem service indicators, time periods, or climate change scenarios, models or variables). While biased and constrained by excluding articles published in non-English languages and grey literature, this data spreadsheet compiles summary information and relevant literature for managers, decision-makers, researchers, and planners.