Menhaden oil was enzymatically modified with caprylic (C8:0) and/or stearic acid (C18:0) to produce structured lipids (SL) with high amount of polyunsaturated fatty acids (PUFA) and melting point of 25-35 degrees centigrade. Linear interpolation was used to determine substrate molar ratios for the reaction. Thermal behavior was determined with DSC and volatile oxidation products by solid phase microextraction (SPME) fiber. The data files are provided in their original .xlsx format, as well as in .csv. The folders are broken down into the following categories: linear interpolation initial experiments (10g, various molar ratios (1:1,1:3, 1:5), and validation under optimal conditions (both 10g and 500g), and finally large-scale reactions (1kg). There is also a folder (“Data”) containing the initial 10g reactions for the caprylic/stearic acid blends (A,B,C).